ID Q833J4_ENTFA Unreviewed; 923 AA.
AC Q833J4;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 136.
DE SubName: Full=Sigma-54 dependent DNA-binding response regulator {ECO:0000313|EMBL:AAO81703.1};
GN OrderedLocusNames=EF_1955 {ECO:0000313|EMBL:AAO81703.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO81703.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO81703.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
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DR EMBL; AE016830; AAO81703.1; -; Genomic_DNA.
DR RefSeq; NP_815633.1; NC_004668.1.
DR RefSeq; WP_002383122.1; NZ_KE136528.1.
DR AlphaFoldDB; Q833J4; -.
DR STRING; 226185.EF_1955; -.
DR EnsemblBacteria; AAO81703; AAO81703; EF_1955.
DR KEGG; efa:EF1955; -.
DR PATRIC; fig|226185.45.peg.1567; -.
DR eggNOG; COG0640; Bacteria.
DR eggNOG; COG1221; Bacteria.
DR eggNOG; COG3933; Bacteria.
DR HOGENOM; CLU_014204_1_0_9; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR32071:SF38; PSP OPERON TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00874; PRD; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR PROSITE; PS51372; PRD_2; 2.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000313|EMBL:AAO81703.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001415};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 106..340
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 448..557
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 558..693
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 814..920
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 923 AA; 105951 MW; FCA1D6F31C6E0EDF CRC64;
MLKTQIVDYL RNQTAFFEPS LVSEIFTASN IATTFSIKRN TASHYLNQLN EEGILVKINT
RPVYFFHKEA FQQQNYLLKR TVYQSFQEMI DEQPVFDRKS DFFQSVIGYR GSLAQTIEQL
KMAALYPGGG LPVLITGESG TGKSFLASLY YQFCLSKELL DDSAPFVTVN CAQYANNPEL
LTSQLFGHLK GAFTGADSDK IGAFQSAEGG VLFLDEVHRL SPEGQEKLFT FLDQGIIYRM
GETNRPIPVT CRLCFATTEE ISSTFLTTFL RRIPIQIKIP SLAERTQAER KQLIMRAFYE
EQQAIQKAVT ITPQVIQLLE NHHYVGNVGE LRNNIKIITA RSFAANLDKC VIPITLHDLP
KEFLDQSIKL VPDENELPIR LDEQTNLVSL LEETELAQRR IIQSYERILR LYVSHHHHLS
TANNDISKEI ERLFDDLLFE KKREKNHEML LFITQNIRQL LETIESSYQI RFNGSLVYAL
STYLFQRRCI DWFPEQEPTT VIDELLTEVQ TKLATSYGYA EQLLTLVKRS LDIELSQMDR
IIVTIYLHYS GSVKKSHYPK AVIVAHGYAT ASSIANVANR LLNVPIFQSF DMPLDVTPKK
ISEHLIHYME RQETRNGLVI LFDMGSLKEI YQYFPAEEEG PFLLMNNVTT SLALSIGEAI
KDEVSFEELP QKALTVHPNE WEIILPENKT ERVILTTCST GIGTAVKIRD LLEKSLPAEA
QLKIIPCEYN QLRNAESIKE SFPEYEIVGI IGTNNPSSND LPYISLEELI AGKGITTLLE
WTKRELTKDM LSYVNHELIR NFSLDRVIQS VTILDTEKII RQVEVFLIQL EERWQQTIQN
DRKLAVYVHV SCLIERLIRN EPIENYNGAE QLKQCQRTVL QELKEAFSVI EKVYSVNIPE
SELFYVYDVL FGKTEFNNAE SDF
//
