ID Q834H3_ENTFA Unreviewed; 477 AA.
AC Q834H3;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Carboxyl-terminal protease {ECO:0000313|EMBL:AAO81457.1};
GN OrderedLocusNames=EF_1679 {ECO:0000313|EMBL:AAO81457.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO81457.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO81457.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- SIMILARITY: Belongs to the peptidase S41A family.
CC {ECO:0000256|ARBA:ARBA00009179, ECO:0000256|RuleBase:RU004404}.
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DR EMBL; AE016830; AAO81457.1; -; Genomic_DNA.
DR RefSeq; NP_815387.1; NC_004668.1.
DR AlphaFoldDB; Q834H3; -.
DR STRING; 226185.EF_1679; -.
DR MEROPS; S41.007; -.
DR EnsemblBacteria; AAO81457; AAO81457; EF_1679.
DR KEGG; efa:EF1679; -.
DR PATRIC; fig|226185.45.peg.1831; -.
DR eggNOG; COG0793; Bacteria.
DR eggNOG; COG3409; Bacteria.
DR HOGENOM; CLU_017295_3_0_9; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00988; PDZ_CTP_protease; 1.
DR CDD; cd07560; Peptidase_S41_CPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004447; Peptidase_S41A.
DR InterPro; IPR002477; Peptidoglycan-bd-like.
DR InterPro; IPR036365; PGBD-like_sf.
DR InterPro; IPR036366; PGBDSf.
DR InterPro; IPR005151; Tail-specific_protease.
DR NCBIfam; TIGR00225; prc; 1.
DR PANTHER; PTHR32060:SF22; CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR32060; TAIL-SPECIFIC PROTEASE; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF01471; PG_binding_1; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47090; PGBD-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004404};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU004404, ECO:0000313|EMBL:AAO81457.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001415};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU004404}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..166
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 477 AA; 51911 MW; 001A6DD2FE9FBF19 CRC64;
MKNKRTVPFY QYIISLLCVA FLAGGSSYIY FDHRVKKMSQ EGAITNADLS KVQDLYNEIS
TNYVGEVDKN ELVEGALKGM SEAIGDPYST YLNESAANDL NESLSGDFEG IGATMTMKDG
EPVVAEAPVA DSPAEKAGIK EGDIIEKVDG TATKGMKLAE VVSKVRGKKG TSVELTIQRE
GETKNISIKR GKIPVKTVTG ELDKNDAQIG SIKITSFGKK TYQELKETIT NLRDKGAKSF
VIDVRQNPGG LLDQAERMAS MFLKNGETIV QFEDKKGRTM KEVASKELDG GFKVKEPVAV
IIDGNSASAS EIFAAALHES ANVPLIGTKT FGKGTVQTVK DLNDQTEIKL TVLKWLTPKG
EWINEKGIEP TIKADYPEYA YLKLIPRDKT LKEGDQSEDI QNLNAILAVL AYPVDENNAN
YTAETKAAVS DLQQKNGLPV TGEIDNETAT KIEATLGKLI LENDAAYDTA VKEIQKN
//
