ID Q83B70_COXBU Unreviewed; 372 AA.
AC Q83B70;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:AAO91141.1};
GN Name=dotB {ECO:0000313|EMBL:AAO91141.1};
GN OrderedLocusNames=CBU_1645 {ECO:0000313|EMBL:AAO91141.1};
OS Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Coxiella.
OX NCBI_TaxID=227377 {ECO:0000313|EMBL:AAO91141.1, ECO:0000313|Proteomes:UP000002671};
RN [1] {ECO:0000313|EMBL:AAO91141.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., Deboy R.T.,
RA Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA Fraser C.M., Heidelberg J.F.;
RT "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN [2] {ECO:0000313|EMBL:AAO91141.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=19047403; DOI=10.1128/IAI.01141-08;
RA Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D.,
RA Williams K.P., Sobral B.W., Kupko J.J.III., Porcella S.F., Samuel J.E.,
RA Heinzen R.A.;
RT "Comparative genomics reveal extensive transposon-mediated genomic
RT plasticity and diversity among potential effector proteins within the genus
RT Coxiella.";
RL Infect. Immun. 77:642-656(2009).
CC -!- SIMILARITY: Belongs to the GSP E family.
CC {ECO:0000256|ARBA:ARBA00006611}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE016828; AAO91141.1; -; Genomic_DNA.
DR RefSeq; NP_820627.1; NC_002971.3.
DR RefSeq; WP_005769572.1; NZ_CCYB01000014.1.
DR AlphaFoldDB; Q83B70; -.
DR STRING; 227377.CBU_1645; -.
DR EnsemblBacteria; AAO91141; AAO91141; CBU_1645.
DR GeneID; 1209556; -.
DR KEGG; cbu:CBU_1645; -.
DR PATRIC; fig|227377.7.peg.1638; -.
DR eggNOG; COG2805; Bacteria.
DR HOGENOM; CLU_013446_4_0_6; -.
DR OrthoDB; 6189814at2; -.
DR Proteomes; UP000002671; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd19516; DotB_TraJ; 1.
DR Gene3D; 3.30.450.90; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013363; Dot_Icm_DotB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001482; T2SS/T4SS_dom.
DR NCBIfam; TIGR02524; dot_icm_DotB; 1.
DR PANTHER; PTHR30486:SF6; CONJUGAL TRANSFER PROTEIN RV3659C-RELATED; 1.
DR PANTHER; PTHR30486; TWITCHING MOTILITY PROTEIN PILT; 1.
DR Pfam; PF00437; T2SSE; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:AAO91141.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AAO91141.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002671}.
FT DOMAIN 136..299
FT /note="Bacterial type II secretion system protein E"
FT /evidence="ECO:0000259|Pfam:PF00437"
SQ SEQUENCE 372 AA; 41336 MW; 1406E092C4E40BDE CRC64;
MIEKSQRYPN EPSRFEPKHI DDLLIYCHRL GASDITIQTG RAVLAEVYGR LQTLTRRELS
NAETSDLLNA IYGPNGTTQI MRGEDIDTHY EIRPNRNERF RYRINGTGCH VDGHEGIQIT
IRAIPAEPPL LSKLDLPAAI VDAIAPQEGV VYVTGATGSG KSTLLAAIIR ELAEAPDSHR
KILTYEAPIE YVYDSLTTPT ASVCQSEIPR HLNSFAAGVR NALRRKPHAI LVGEARDNET
ISAVLEAALT GHPVYTTLHS SGVAETIRRL VGSFPAEERI GRTIDIIETL RLIIWQRLVP
SVDGKRVALR EFLVFKEEIR DLLLDSDPEQ ITAAVRRLVA EHGQPMQVDV EAKFKGGLIS
ERLYKILSAS QE
//
