ID Q83C74_COXBU Unreviewed; 267 AA.
AC Q83C74;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Dimethylallyltransferase {ECO:0000313|EMBL:AAO90763.1};
DE EC=2.5.1.1 {ECO:0000313|EMBL:AAO90763.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:AAO90763.1};
DE EC=2.5.1.29 {ECO:0000313|EMBL:AAO90763.1};
GN OrderedLocusNames=CBU_1255 {ECO:0000313|EMBL:AAO90763.1};
OS Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Coxiella.
OX NCBI_TaxID=227377 {ECO:0000313|EMBL:AAO90763.1, ECO:0000313|Proteomes:UP000002671};
RN [1] {ECO:0000313|EMBL:AAO90763.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., Deboy R.T.,
RA Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA Fraser C.M., Heidelberg J.F.;
RT "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN [2] {ECO:0000313|EMBL:AAO90763.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=19047403; DOI=10.1128/IAI.01141-08;
RA Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D.,
RA Williams K.P., Sobral B.W., Kupko J.J.III., Porcella S.F., Samuel J.E.,
RA Heinzen R.A.;
RT "Comparative genomics reveal extensive transposon-mediated genomic
RT plasticity and diversity among potential effector proteins within the genus
RT Coxiella.";
RL Infect. Immun. 77:642-656(2009).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; AE016828; AAO90763.1; -; Genomic_DNA.
DR RefSeq; NP_820249.1; NC_002971.3.
DR RefSeq; WP_010958105.1; NC_002971.4.
DR AlphaFoldDB; Q83C74; -.
DR STRING; 227377.CBU_1255; -.
DR EnsemblBacteria; AAO90763; AAO90763; CBU_1255.
DR GeneID; 1209160; -.
DR KEGG; cbu:CBU_1255; -.
DR PATRIC; fig|227377.7.peg.1246; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_1_6; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000002671; Chromosome.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004311; F:farnesyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004659; F:prenyltransferase activity; IBA:GO_Central.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000002671};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:AAO90763.1}.
SQ SEQUENCE 267 AA; 29694 MW; 8CD52A6E85A496C2 CRC64;
MNVITIYQER INHKLGSILP DIRQTPQRLH EAMTYAVMSG GKRIRPLFTY ATGFSFEVDP
AQIDNAACAI ELMHCYSLVH DDLPAMDDDD FRRGKPSCHK AFDEATAILT GDALQCLAFE
VLARDKNIRL INVLANACGS LGMAGGQQLD LEFKNKEATP EQIEIVHRLK TGALFSTAIE
LGALAAGCLD EKRLQKLRKL GATVGLIFQW QDDLADQTVE DEKIPLINRI GVLFNQVEKL
LNELEGNNSF LQELIHFLKS SITAVIQ
//
