ID Q83CN8_COXBU Unreviewed; 385 AA.
AC Q83CN8;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 140.
DE SubName: Full=Queuine tRNA-ribosyltransferase {ECO:0000313|EMBL:AAO90585.1};
DE EC=2.4.2.29 {ECO:0000313|EMBL:AAO90585.1};
GN Name=tgt {ECO:0000313|EMBL:AAO90585.1};
GN OrderedLocusNames=CBU_1072 {ECO:0000313|EMBL:AAO90585.1};
OS Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Coxiella.
OX NCBI_TaxID=227377 {ECO:0000313|EMBL:AAO90585.1, ECO:0000313|Proteomes:UP000002671};
RN [1] {ECO:0000313|EMBL:AAO90585.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., Deboy R.T.,
RA Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA Fraser C.M., Heidelberg J.F.;
RT "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN [2] {ECO:0000313|EMBL:AAO90585.1, ECO:0000313|Proteomes:UP000002671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSA 493 / Nine Mile phase I
RC {ECO:0000313|Proteomes:UP000002671};
RX PubMed=19047403; DOI=10.1128/IAI.01141-08;
RA Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D.,
RA Williams K.P., Sobral B.W., Kupko J.J.III., Porcella S.F., Samuel J.E.,
RA Heinzen R.A.;
RT "Comparative genomics reveal extensive transposon-mediated genomic
RT plasticity and diversity among potential effector proteins within the genus
RT Coxiella.";
RL Infect. Immun. 77:642-656(2009).
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DR EMBL; AE016828; AAO90585.1; -; Genomic_DNA.
DR RefSeq; NP_820071.1; NC_002971.3.
DR RefSeq; WP_010957987.1; NC_002971.4.
DR AlphaFoldDB; Q83CN8; -.
DR STRING; 227377.CBU_1072; -.
DR EnsemblBacteria; AAO90585; AAO90585; CBU_1072.
DR GeneID; 1208973; -.
DR KEGG; cbu:CBU_1072; -.
DR PATRIC; fig|227377.7.peg.1064; -.
DR eggNOG; COG0343; Bacteria.
DR HOGENOM; CLU_022060_0_2_6; -.
DR OrthoDB; 9805417at2; -.
DR Proteomes; UP000002671; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008479; F:tRNA-guanosine(34) queuine transglycosylase activity; IEA:InterPro.
DR GO; GO:0008616; P:queuosine biosynthetic process; IBA:GO_Central.
DR GO; GO:0002099; P:tRNA wobble guanine modification; IBA:GO_Central.
DR GO; GO:0101030; P:tRNA-guanine transglycosylation; IEA:InterPro.
DR Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR InterPro; IPR004803; TGT.
DR InterPro; IPR036511; TGT-like_sf.
DR InterPro; IPR002616; tRNA_ribo_trans-like.
DR NCBIfam; TIGR00430; Q_tRNA_tgt; 1.
DR NCBIfam; TIGR00449; tgt_general; 1.
DR PANTHER; PTHR46499; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR46499:SF1; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR Pfam; PF01702; TGT; 1.
DR SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:AAO90585.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002671};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AAO90585.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 18..381
FT /note="tRNA-guanine(15) transglycosylase-like"
FT /evidence="ECO:0000259|Pfam:PF01702"
SQ SEQUENCE 385 AA; 42632 MW; 90E59F79C1E6532E CRC64;
MQNTFKTEII QRSKTNHARV TKITTPHGEV VTPAFMPVGT RAFANHLTPH DLVAAHSQII
LGGNTYHMLV APGLEVIQAA GGMHAFMGWD KPMLTDSGGF QVFSLSKNRE ICTFDEEGAH
FKHPTTGKLI HLTPKSSIDT QKAIGADIIM AFDECTPENG GREAALGALQ RTHYWLAKSK
QAHLQSPCSL YGHRQALFGI IQGGSFRDLR EKSAQSVVDM DLDGIAIGGE VIGFDMAKTC
QIIDWVRPLL PEGKTRYAMG VGLSPQDLID VVAAGVDIFD CVAPTRNARH GALYHGHCVV
ENGWVRFISE QENGRIQIKK SIYAKDETPL LAGCRCYTCQ HFCRAYLHYL FKQKSTLYAQ
LACIHNIHVM QETCCFLRQL IVQVQ
//
