ID   Q83GG4_TROWT            Unreviewed;       313 AA.
AC   Q83GG4;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Serine-type D-Ala-D-Ala carboxypeptidase {ECO:0000313|EMBL:AAO44424.1};
DE            EC=3.4.16.4 {ECO:0000313|EMBL:AAO44424.1};
GN   Name=dacB {ECO:0000313|EMBL:AAO44424.1};
GN   OrderedLocusNames=TWT_327 {ECO:0000313|EMBL:AAO44424.1};
OS   Tropheryma whipplei (strain Twist) (Whipple's bacillus).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Tropherymataceae;
OC   Tropheryma.
OX   NCBI_TaxID=203267 {ECO:0000313|EMBL:AAO44424.1, ECO:0000313|Proteomes:UP000002200};
RN   [1] {ECO:0000313|EMBL:AAO44424.1, ECO:0000313|Proteomes:UP000002200}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Twist {ECO:0000313|EMBL:AAO44424.1,
RC   ECO:0000313|Proteomes:UP000002200};
RX   PubMed=12902375; DOI=10.1101/gr.1474603;
RA   Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M.,
RA   Claverie J.-M.;
RT   "Tropheryma whipplei twist: a human pathogenic Actinobacteria with a
RT   reduced genome.";
RL   Genome Res. 13:1800-1809(2003).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE014184; AAO44424.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q83GG4; -.
DR   STRING; 203267.TWT_327; -.
DR   MEROPS; S11.002; -.
DR   KEGG; twh:TWT_327; -.
DR   eggNOG; COG1686; Bacteria.
DR   HOGENOM; CLU_888359_0_0_11; -.
DR   OrthoDB; 5241551at2; -.
DR   Proteomes; UP000002200; Chromosome.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001967; Peptidase_S11_N.
DR   Pfam; PF00768; Peptidase_S11; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Carboxypeptidase {ECO:0000313|EMBL:AAO44424.1};
KW   Hydrolase {ECO:0000313|EMBL:AAO44424.1};
KW   Protease {ECO:0000313|EMBL:AAO44424.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002200}.
FT   DOMAIN          79..270
FT                   /note="Peptidase S11 D-alanyl-D-alanine carboxypeptidase A
FT                   N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00768"
SQ   SEQUENCE   313 AA;  35088 MW;  3B260453B37D43C8 CRC64;
     MRLYRPLFYA CLLLSFLFFI LSDRYGMERT QSPHTVDISQ RYFADSSLSL LPHLLDPDIK
     HIALDVDGHP ELKLRKGNKG KHPIASISKV ILALMLIERY SLSELNDGPN ITYDTEDVSF
     FRNSVKDGDS YAPVYAGLTL TLKQSLIPLM LPSANNYATS LVKHLYGKSY PKFAREWLDK
     NGLYNTDIYE ASGLDDRNVS TADNLIVLAK KAYSNPVLRG IMRLKEASIP NIGLVRNTNK
     ALGINGIDGI KTGSSPAAKS NLLFTAAIKT KNGLIRIYGV FKTEKSYASL YGKLDTLLKR
     VRAYFHQRNL LTD
//