ID Q86AR1_DICDI Unreviewed; 1163 AA.
AC Q86AR1; Q550C2;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 136.
DE RecName: Full=C3H1-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DDB_G0277217 {ECO:0000313|EMBL:EAL68794.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL68794.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL68794.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL68794.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL68794.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL68794.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL68794.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFI02000019; EAL68794.1; -; Genomic_DNA.
DR RefSeq; XP_642694.1; XM_637602.1.
DR AlphaFoldDB; Q86AR1; -.
DR SMR; Q86AR1; -.
DR STRING; 44689.Q86AR1; -.
DR PaxDb; 44689-DDB0169078; -.
DR GeneID; 8620884; -.
DR KEGG; ddi:DDB_G0277217; -.
DR dictyBase; DDB_G0277217; -.
DR eggNOG; KOG2135; Eukaryota.
DR HOGENOM; CLU_275016_0_0_1; -.
DR InParanoid; Q86AR1; -.
DR OMA; ITYDSHA; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd12257; RRM1_RBM26_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045137; RBM26/27.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF0; ZINC FINGER PROTEIN SWM; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 311..339
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 585..656
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT ZN_FING 311..339
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 81..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..872
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1102
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1155
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1163 AA; 135114 MW; F824538AA84841E9 CRC64;
MVELTEDPEF SKFLIQTLDP ICEFDPSSLS DYIKEFLSNG FQTRKDLEET FSKDLEDFLH
ENTKSFINTL VSKLNSTNYF SKSTTSPIIS PSNITITNRD SRERERERER ENRDRSDRDR
GERERERERD RERDRDRDRL ERERDRDRDR DRERERDRER DRNKDRERDR ERERDRERDR
DRDRNRNSRE RDHNDRDYNN NSSSSSSSSN RYRERERERE RERSISPSSS SLTTHTRKRS
RSRSNSPQPL DEFNNNNNNN NNNNNNNNNN NNNMTGNNTY RNGSGANRFK RRSTNDEFNN
NNNNNSFKKF PKSTRICKYI EKNGICTRGD SCNFSHDLSL LNNNNNNNNN NNNNIDMINN
NNQNMNNNNN NNNNNGYMYN GGNFNDFDNN NNNNFRKFNN RFDDDNNNNN NNNNFNIPVN
NVSDNNSPPF PFDNANISPN QMIFSSFNNN NNNNNNNINN NQPSFSMMDQ NQMYIGQMNQ
NQMDFNNHNN NNNNNNMDFN NMDFNINNNN NNNNIYNNNN NNNNNNNINN NNNNNINNNN
NSNNYNNEDD EEFNDFQNNN NNNNRGNKQY DNIKTSSNCP SSESTKLVIT NIPLQQNIEE
EIREHFSKFG TITNITKLST AKSMIEFSNN SEAMKAMKSP EAIMNNRFIK LFWEDSFDHA
TAKKTKFEEQ QEKQEQIQKK KEEKEKRDQD LMKIREQQLL KKLEDRKKLL EKQSEKKKEL
VLVVKSREEL RNQQLDLQKQ LLTKLAICKD EKEKDAIKES IKQLTKSITE SLQKDQQTTN
QLNQLNSTTS AAATTTTTTT TTASTVLIPP STSTSTSTPQ PSTSTTITTL NNISTPTTPM
PTTPTTPTTP TTPTTPTSTS IEIEGAPGSG NIEQLSNTLK ELESEAKSLG IDPNTITSAA
TATTTITSIP TTTTTTTPII PNKPNFKKLP PRLVAQKPII AKKPKNNSIL IDNTTTTIQI
IDPPLEFKNE SLLKQLFTDI ESVIQEENSI QIKFGKRQSA ERVFVVAKVY KGKSLNIQWV
QDKEKQLLPQ FSKQQLPQLP QQQLSQLQQK LQQQQQQILA KQLQQKQQLQ SQFKQTIKEK
SSDDEFDEDA YDNQDEDAAD NMNDDNNNNN NNENQDEEEQ DYEEIPTETI LKSGSNINNN
ANDDDDDDDE DDYDEDDKPS WKH
//
