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Database: UniProt
Entry: Q87109_SIVSA
LinkDB: Q87109_SIVSA
Original site: Q87109_SIVSA 
ID   Q87109_SIVSA            Unreviewed;       234 AA.
AC   Q87109;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   10-FEB-2021, entry version 83.
DE   RecName: Full=Virion infectivity factor {ECO:0000256|RuleBase:RU003341};
OS   Simian immunodeficiency virus - agm.sab-1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=349974 {ECO:0000313|EMBL:AAA21506.1, ECO:0000313|Proteomes:UP000260447};
RN   [1] {ECO:0000313|EMBL:AAA21506.1, ECO:0000313|Proteomes:UP000260447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SIVagmSAB-1 {ECO:0000313|EMBL:AAA21506.1,
RC   ECO:0000313|Proteomes:UP000260447};
RX   PubMed=8026477;
RA   Jin M.J., Hui H., Robertson D.L., Muller M.C., Barre-Sinoussi F.,
RA   Hirsch V.M., Allan J.S., Shaw G.M., Sharp P.M., Hahn B.H.;
RT   "Mosaic genome structure of simian immunodeficiency virus from west African
RT   green monkeys.";
RL   EMBO J. 13:2935-2947(1994).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Host cell membrane
CC       {ECO:0000256|ARBA:ARBA00004501, ECO:0000256|RuleBase:RU003341};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004501,
CC       ECO:0000256|RuleBase:RU003341}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004501, ECO:0000256|RuleBase:RU003341}. Host
CC       cytoplasm {ECO:0000256|RuleBase:RU003341}. Virion
CC       {ECO:0000256|RuleBase:RU003341}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}. Note=In the cytoplasm, seems to
CC       colocalize with intermediate filament vimentin. A fraction is
CC       associated with the cytoplasmic side of cellular membranes, presumably
CC       via the interaction with Pr55Gag precursor.
CC       {ECO:0000256|RuleBase:RU003341}.
CC   -!- SIMILARITY: Belongs to the primate lentivirus group Vif protein family.
CC       {ECO:0000256|ARBA:ARBA00006372, ECO:0000256|RuleBase:RU003341}.
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DR   EMBL; U04005; AAA21506.1; -; Genomic_DNA.
DR   SMR; Q87109; -.
DR   Proteomes; UP000260447; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
DR   GO; GO:0019058; P:viral life cycle; IEA:InterPro.
DR   InterPro; IPR000475; Vif.
DR   Pfam; PF00559; Vif; 1.
DR   PRINTS; PR00349; VIRIONINFFCT.
PE   3: Inferred from homology;
KW   Host cytoplasm {ECO:0000256|ARBA:ARBA00023200};
KW   Reference proteome {ECO:0000313|Proteomes:UP000260447};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   REGION          164..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..180
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   234 AA;  27603 MW;  66CCB430547DBAF2 CRC64;
     MEKHWIVRPL WKVTGGQQER WTSLVKYHMH VSKQCVHWRY TPHTKIRWNW YSYQEWVIPL
     KDGALIKVTN YWHLTPEKGW LETYATGIGY SKGEWFTELD PWTADHIIHW SYFPCFTDRA
     VQQAIRGEKY LWCKHQVGHQ PTGQVPSLQY LALRVYTNGL RRVAPTSRRG SSQGSPQESQ
     RRDTRMARNM GFAQRAVRRM APRHVTGPQF RGPVPLPKES PFPSLVEYCG RTSH
//
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