ID   Q87G08_VIBPA            Unreviewed;       774 AA.
AC   Q87G08;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=ScrC (Sensory box/GGDEF family protein) (Involved in swarmer cell regulation) {ECO:0000313|EMBL:BAC62854.1};
GN   OrderedLocusNames=VPA1511 {ECO:0000313|EMBL:BAC62854.1};
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC62854.1, ECO:0000313|Proteomes:UP000002493};
RN   [1] {ECO:0000313|EMBL:BAC62854.1, ECO:0000313|Proteomes:UP000002493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX   PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
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DR   EMBL; BA000032; BAC62854.1; -; Genomic_DNA.
DR   RefSeq; NP_801021.1; NC_004605.1.
DR   RefSeq; WP_005478021.1; NC_004605.1.
DR   AlphaFoldDB; Q87G08; -.
DR   SMR; Q87G08; -.
DR   GeneID; 1192207; -.
DR   KEGG; vpa:VPA1511; -.
DR   PATRIC; fig|223926.6.peg.4435; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_91_4_6; -.
DR   Proteomes; UP000002493; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002493};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        279..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          377..510
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          519..772
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          305..332
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   774 AA;  88233 MW;  3BA784406710B7D8 CRC64;
     MKKAVKKISS KKIITISAII VSIYLAILIV VTSLGQNKLK DSQYRELDLK VKSYASTLDN
     LFTIASEDVD NLSSDKTVQT FFANLASGMS MEYGLGASLI NLKRRFDEKI DGKLINSSNI
     YNKLTLVGSD GTTIVTTGPK DLKPMDIHDL MTQHGHPEEV CATRDGDNIR IQVIKQVKFS
     GKPVAFLIAD INKDIVIEQL TNQEHEDSYS RMVLKIKDVE MVVWDSITKN STINADENHF
     LSKILDGKIY FEVPVEQHHF KLMAWFEPLN ERDIFTSRLF IVGLSILAVM IVIALCYAFV
     TNNNKLELKI KLEEEKKRKD ILSQQNHKLT KEIERRKASE KELAFQAKYD TLTELPNRSY
     GSERLALELI RASRTGSKVL VMFIDLDHFK QINDSMGHFV GDEILKLSAQ RLQNVARKTD
     LLARIGGDEF LLVIPDLPDN DTAKRVASSV LSAFSEPFVW NNHEFFLTGS VGMSVFPDDG
     DNAEQLLACA DMAMYRVKQD GRDAFCFYNH NMNQDLQRYL DLESRLRNAI SNQLLEMYYQ
     PIIELKSGKI VGAEALMRWN DEKFGFVNPE EFISIAEKNG LIHQLGEFAI QQACHQASQW
     QSISPLFVSV NFSSVQFRYC DRLLAFIRQS LEESGLPAEQ FDVEVTESLL FNHDDELVDM
     LDNLRALGTK LTIDDFGTGY SALSYLQKFP FDRLKIDRSF MQNVFENDSD RELVNVIIAM
     AKALRLKIVA EGIEEQRHVD YLNELNCEFG QGFHYSRPVP AKEFEQLLNQ PTWS
//