ID Q87LY5_VIBPA Unreviewed; 371 AA.
AC Q87LY5;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN OrderedLocusNames=VP2473 {ECO:0000313|EMBL:BAC60736.1};
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC60736.1, ECO:0000313|Proteomes:UP000002493};
RN [1] {ECO:0000313|EMBL:BAC60736.1, ECO:0000313|Proteomes:UP000002493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; BA000031; BAC60736.1; -; Genomic_DNA.
DR RefSeq; NP_798852.1; NC_004603.1.
DR RefSeq; WP_005479099.1; NC_004603.1.
DR AlphaFoldDB; Q87LY5; -.
DR SMR; Q87LY5; -.
DR GeneID; 1189988; -.
DR KEGG; vpa:VP2473; -.
DR PATRIC; fig|223926.6.peg.2373; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_0_1_6; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF29; BLR2860 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002493}.
FT DOMAIN 67..274
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 371 AA; 40106 MW; EF7921F4D40B2840 CRC64;
MSGTSFGRRF VERPWLVSLI LILLLVAWLA AGQLKAQGDH TLSPSLQSEN TPLAKVMFDT
FTAKPTSKTI ELYGRTAPNR QARLGAEVAG KIVSLSINKG QLVKQGQVIA NIDKRDLDSQ
LKRAQAMLRV KEKEFNAAKS LKSRGLQGEV AFATAEAALV DARANLNNVQ TALKNTEVKA
PFDGIVDHHF VEVGDFVGVG DPIATVIDLE TLVIEADVSE RHIQYLKEGL QADVRTINGQ
HHLGTLRYIG RVSSVSTNTF PIEIEIDNRN SLIPAGISAE VQLPLNEVLA IKITAAMLAL
DEEGNLGVKT LQDEHVKFVP IQLVKAEEDG VWLSGLGEQA DIIVLGQGFV RDGETVIANK
VGDVAADAAE K
//
