ID   Q87TJ7_VIBPA            Unreviewed;      1046 AA.
AC   Q87TJ7;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=Sensory box/GGDEF family protein {ECO:0000313|EMBL:BAC58335.1};
GN   OrderedLocusNames=VP0071 {ECO:0000313|EMBL:BAC58335.1};
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC58335.1, ECO:0000313|Proteomes:UP000002493};
RN   [1] {ECO:0000313|EMBL:BAC58335.1, ECO:0000313|Proteomes:UP000002493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX   PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
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DR   EMBL; BA000031; BAC58335.1; -; Genomic_DNA.
DR   RefSeq; NP_796451.1; NC_004603.1.
DR   RefSeq; WP_005478687.1; NC_004603.1.
DR   AlphaFoldDB; Q87TJ7; -.
DR   GeneID; 1187539; -.
DR   KEGG; vpa:VP0071; -.
DR   PATRIC; fig|223926.6.peg.68; -.
DR   eggNOG; COG2984; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_32_0_6; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002493};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        337..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          441..493
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          494..548
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          648..781
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          792..1046
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   1046 AA;  120524 MW;  918AB439BDA9DB38 CRC64;
     MQRFLILVAF FWSACAWSEL TLAQEPKVLV VHSYHQGFFW TDSIQRGIDQ QLDDREMDMR
     VLYLDSKRNQ SEQFFTQLES LYRTKLSDER FDAILVTDNN ALELMQHLAP LIKDTPVIFC
     GINNYRPSFH QSLNATGVIE NVDLEANLAL IERLHPDNKQ IYIISDHSVT GAILRDEIDD
     FIQQHDRYRN KITQLVPDNV EALKKKIAQL NKENVVLFWT YYRDKDGVVG SERDWIQINK
     ASNAPLFMVH DVGLGHGAVG GVIQSGYRQG VEAARLLEQV LDHPQEPLPP VVNGDSEIKL
     DYQAVVRWGL GAEQESSAVF FNKPMEFSER FAKEIRLFGS LFVLMLVAIL LLSYYLQRIR
     RSETAARESQ AILESIFDQS MQYMGILDKH GLLKSGNDRL QSLLYHQELR LDKPLWLHQN
     WSEQARHAIA DYFDAPQQQV STFEAEIWSK EHGSMVLEIS LKPFSQQVGK QKQYLFEARD
     ITSRKLMEDK LYQRESSLRN YYEQQPVMMV TLDSHNRIQE VNRFAQLLLG YEPIEMLGHR
     LREFYLDDKA LFPRQVLLQP SHQVHDVWRR EIEYRHADGH SVWVRENIRP LNDSDQLLIV
     GEDISETKLL AEKLEYQARY DLLTGTYNRN HFELELKTAL REVDSHRRVH AMLYLDLDQL
     KVLNDTVGHD AGDAAIQFCA SMLEEVLPYN SVLARMGGDE FAVLLKDCDE YGAINIAKVI
     ISTLGEHLFI WEDTRLFISC SVGIRIIDHT AETPQMVHAQ ADSACHAAKE QGRNRYNLFS
     LDNEELQRRQ MEMQSVNLVH EALSNQRLEL FAQRVMNLQS PESLMYFEIL VRIRDAQGNY
     VSPAIFIPAS ERYNIAHWID KQVINQALEW FEQRPDVVEK LGRCSINLSG QSMGNQEFID
     FLFERLKNST MPCEKICLEI TETAAMGNLD QAIDFFTRAK SLGCMIALDD FGSGLSSFGY
     LKKLPVDIVK IDGLFVRDID VNEMDRVMVR SINDLAKQLG KVTVAEFVEN EQVMQHLIDL
     GVDYGQGYGI GHPKPLAELV ENLSSL
//