ID Q87XU6_PSESM Unreviewed; 1161 AA.
AC Q87XU6;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=PSPTO_4079 {ECO:0000313|EMBL:AAO57536.1};
OS Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=223283 {ECO:0000313|EMBL:AAO57536.1, ECO:0000313|Proteomes:UP000002515};
RN [1] {ECO:0000313|EMBL:AAO57536.1, ECO:0000313|Proteomes:UP000002515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-871 / DC3000 {ECO:0000313|Proteomes:UP000002515};
RX PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA Gwinn M.L., Dodson R.J., Deboy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Daugherty S., Brinkac L., Beanan M.J., Haft D.H., Nelson W.C., Davidsen T.,
RA Zafar N., Zhou L., Liu J., Yuan Q., Khouri H., Fedorova N., Tran B.,
RA Russell D., Berry K., Utterback T., Van Aken S.E., Feldblyum T.V.,
RA D'Ascenzo M., Deng W.L., Ramos A.R., Alfano J.R., Cartinhour S.,
RA Chatterjee A.K., Delaney T.P., Lazarowitz S.G., Martin G.B.,
RA Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M., Collmer A.;
RT "The complete genome sequence of the Arabidopsis and tomato pathogen
RT Pseudomonas syringae pv. tomato DC3000.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE016853; AAO57536.1; -; Genomic_DNA.
DR RefSeq; NP_793841.1; NC_004578.1.
DR AlphaFoldDB; Q87XU6; -.
DR STRING; 223283.PSPTO_4079; -.
DR KEGG; pst:PSPTO_4079; -.
DR PATRIC; fig|223283.9.peg.4181; -.
DR eggNOG; COG1457; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_008084_1_0_6; -.
DR OrthoDB; 9810730at2; -.
DR PhylomeDB; Q87XU6; -.
DR Proteomes; UP000002515; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AAO57536.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000002515};
KW Transferase {ECO:0000313|EMBL:AAO57536.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 83..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 726..941
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 964..1075
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 1013
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1161 AA; 129344 MW; D44DDB52A06A7E26 CRC64;
MIAHLRKPRA WILLAFVVQR LFYQGASNDL LPLLWRRTVR PSGSQRIIKI RRDYNRLVAD
ETMEDYALRF TPKSFRKWSE WRISNTAVGA VSFLALEAIG GALVISYGFT NTLWAILATA
LVIFLTGLPI SYYAARYGVD MDLLTRGAGF GYIGSTITSL IYASFTFLFF ALEAAIMALA
LELYFHIPIA LAYIICSIIV IPLAVYGVTL ISRLQMWSQP LWLTLLLVPY VFVIWKNPDA
LGDWLSFSGR EGEGGTFDLL FFGAAFSVAL SLVTQIGEQV DYLRFLPEKT RHNRKRWWAA
LLMAGPGWII PGALKIMAGA FLAFLALQHE VPVERAAEPT QMYLVAFRYV FSSPEWALAA
MTLFVIISQI KINMTNAYAG SLAWSNFFVR VTHSHPGRVV WLVFNVAIAL VLMELGVFDA
IEQVLGLYAN VAIAWIGALV ADLVINKPMG WSPKHIEFKR AHLYDINPVG VGAMSIASLV
SFCAHFGLFG AIAQAAPPLI SLAIALVTAP LLAWLTDGKY YIARTSSDTL LYPQGRQESL
LCGLCNNAFE TPDMAYCPAY RTPICSLCCS LDARCGDQCK PRARLSMQFE DLIGKVLPRF
PRHYLHTRLA QYLGLLTILV AGSSGALALI YNQVAHGLID QSPEAHHLLM LAFLKAFLTV
CVFAGVLAWW VVLTRESRRV AQEESERQTS LLIQEIDAHE KTDQALQKAK EASEAANAAK
SRYITGLSHE LRTPLNSILG FTQILQRDTT TPPHHQDPLA TIMRSSSHLL SLINGLLDVA
KIEAGKLKLE PTEILFQEFL HDLEKMFAGT AQEKNLGFRL ELEGRMPMVV RGDEKRVRQI
LINLLGNAVN FTDSGEVVLR VSYRRETAIF DIVDSGIGIA PEQIERIFQP FERGGQTRHD
NGVGLGLTIT RMLTALMGGA LSVSSTPGEG THFKVRLFLS EVRVPKAVID VNHDVVGYDG
ERRLVLVVDD HIEHRKVISG MLEPLGFTVA QAENGMEAVR QVSLLHPDLI LMDLSMPDMD
GWATLRMIRR NARSNAPVIV LSANANASTD DDIGHDYLSK PVHLRDLLDR LKHHLNLNWQ
HRSRTASETK TPWILPPRED LEDLYTLCGL GYVRGIQNKL DAIETSNIAS GSFVTDLRAL
AKGFRLDELS LHLKEMLDER P
//
