ID Q87Z85_PSESM Unreviewed; 225 AA.
AC Q87Z85;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=PSPTO_3545 {ECO:0000313|EMBL:AAO57020.1};
OS Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=223283 {ECO:0000313|EMBL:AAO57020.1, ECO:0000313|Proteomes:UP000002515};
RN [1] {ECO:0000313|EMBL:AAO57020.1, ECO:0000313|Proteomes:UP000002515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-871 / DC3000 {ECO:0000313|Proteomes:UP000002515};
RX PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA Gwinn M.L., Dodson R.J., Deboy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Daugherty S., Brinkac L., Beanan M.J., Haft D.H., Nelson W.C., Davidsen T.,
RA Zafar N., Zhou L., Liu J., Yuan Q., Khouri H., Fedorova N., Tran B.,
RA Russell D., Berry K., Utterback T., Van Aken S.E., Feldblyum T.V.,
RA D'Ascenzo M., Deng W.L., Ramos A.R., Alfano J.R., Cartinhour S.,
RA Chatterjee A.K., Delaney T.P., Lazarowitz S.G., Martin G.B.,
RA Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M., Collmer A.;
RT "The complete genome sequence of the Arabidopsis and tomato pathogen
RT Pseudomonas syringae pv. tomato DC3000.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; AE016853; AAO57020.1; -; Genomic_DNA.
DR RefSeq; NP_793325.1; NC_004578.1.
DR RefSeq; WP_003378111.1; NC_004578.1.
DR AlphaFoldDB; Q87Z85; -.
DR STRING; 223283.PSPTO_3545; -.
DR GeneID; 1185210; -.
DR KEGG; pst:PSPTO_3545; -.
DR PATRIC; fig|223283.9.peg.3634; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_2_0_6; -.
DR OrthoDB; 9792284at2; -.
DR PhylomeDB; Q87Z85; -.
DR Proteomes; UP000002515; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002515};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 25..221
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
FT REGION 45..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 225 AA; 23952 MW; 2A8CB59151C21000 CRC64;
MKILMVLTSH DQLGDTGKKT GFWLEEFAAP YYVFKDAGAE VTLVSPAGGQ PPLDPKSDEP
DAQTAETERF AKDADAQKVL ANTGLLAEVN AADFDAVFYP GGHGPLWDLA EDQHSIALIE
AFAKADKPHG LVCHAPGVLR KVKAQNGEPL VKGRRVTGFT NSEEEAVGLT DVVPFLVEDA
LKELGGDYSK GDDWSVYVLT DGKLVTGQNP ASSAQAAKDV LTLLS
//
