ID Q88HD1_PSEPK Unreviewed; 538 AA.
AC Q88HD1;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=PP_3429 {ECO:0000313|EMBL:AAN69031.1};
OS Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS / KT2440).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=160488 {ECO:0000313|EMBL:AAN69031.1, ECO:0000313|Proteomes:UP000000556};
RN [1] {ECO:0000313|EMBL:AAN69031.1, ECO:0000313|Proteomes:UP000000556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440
RC {ECO:0000313|Proteomes:UP000000556};
RX PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA Martins dos Santos V.A., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA Brinkac L., Beanan M., DeBoy R.T., Daugherty S., Kolonay J., Madupu R.,
RA Nelson W., White O., Peterson J., Khouri H., Hance I., Chris Lee P.,
RA Holtzapple E., Scanlan D., Tran K., Moazzez A., Utterback T., Rizzo M.,
RA Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D.,
RA Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N.,
RA Dusterhoft A., Tummler B., Fraser C.M.;
RT "Complete genome sequence and comparative analysis of the metabolically
RT versatile Pseudomonas putida KT2440.";
RL Environ. Microbiol. 4:799-808(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; AE015451; AAN69031.1; -; Genomic_DNA.
DR RefSeq; NP_745567.1; NC_002947.4.
DR RefSeq; WP_010954295.1; NC_002947.4.
DR AlphaFoldDB; Q88HD1; -.
DR STRING; 160488.PP_3429; -.
DR PaxDb; 160488-PP_3429; -.
DR GeneID; 83679863; -.
DR KEGG; ppu:PP_3429; -.
DR PATRIC; fig|160488.4.peg.3645; -.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_000445_114_51_6; -.
DR OrthoDB; 6973808at2; -.
DR PhylomeDB; Q88HD1; -.
DR BioCyc; PPUT160488:G1G01-3662-MONOMER; -.
DR Proteomes; UP000000556; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AAN69031.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000000556};
KW Transferase {ECO:0000313|EMBL:AAN69031.1}.
FT DOMAIN 178..400
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 420..535
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 470
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 538 AA; 58704 MW; 5A4115555FA3087D CRC64;
MASSLALDER ALILAPPQLA ADTSRLLSSA GINSLCAVDL ANLQARLTEG AGLAIIAEQV
FSQGPSTLLQ AFIDQQPSWS DLPIVLLTQG AWSAAGVNHH PVGNLLWLVT PYENAQLLHM
TQSALRNRRR QYVTRDQLHG MQQRLDSRPS TPEEVQDRGE FARCQARKME AIGQLAGGVA
HDFNNLLTSI SGSFELIQRR LRQGRSDGLD GVLCMGREAV SRAARLTHRL LAFSSRQSLH
SQRIDLHTLL KAERLGARLS PSITLQVHAA KDLWPVEADD QQLQEALDNL LLNAREAMPN
GGLLRIEANN HHIATEQAAD GALRTGDYVR LRITDSGQGM AQSTLEHAFE PFFSTKATGQ
GIGLGLSMVY GFSKQSHGHI TLSSEIGQGT QVELYLPRHV DQALSYSEPV PARQDGCSRH
VLVVEDDPHV RQLLCQALGE NGFPCQSAAD ANEGLKVLRS AQPVDLLITD VGLPGMNGRQ
LAEIARSLRP RLPVLFITGY AETAMAREGF LGADMHLICK PFELQQLQAR VTHILGKP
//
