ID Q893I1_CLOTE Unreviewed; 275 AA.
AC Q893I1;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Putative regulator of efflux transporter {ECO:0000313|EMBL:AAO36361.1};
GN OrderedLocusNames=CTC_01842 {ECO:0000313|EMBL:AAO36361.1};
OS Clostridium tetani (strain Massachusetts / E88).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=212717 {ECO:0000313|EMBL:AAO36361.1, ECO:0000313|Proteomes:UP000001412};
RN [1] {ECO:0000313|EMBL:AAO36361.1, ECO:0000313|Proteomes:UP000001412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Massachusetts / E88 {ECO:0000313|Proteomes:UP000001412};
RX PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA Brueggemann H., Baumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I.,
RA Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
RT "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT disease.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE015927; AAO36361.1; -; Genomic_DNA.
DR RefSeq; WP_011100021.1; NC_004557.1.
DR AlphaFoldDB; Q893I1; -.
DR STRING; 212717.CTC_01842; -.
DR GeneID; 24252806; -.
DR KEGG; ctc:CTC_01842; -.
DR HOGENOM; CLU_065103_0_0_9; -.
DR OrthoDB; 9773308at2; -.
DR Proteomes; UP000001412; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd04782; HTH_BltR; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.20.80.10; Regulatory factor, effector binding domain; 1.
DR InterPro; IPR010499; AraC_E-bd.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR029442; GyrI-like.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR011256; Reg_factor_effector_dom_sf.
DR PANTHER; PTHR30204:SF87; MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF06445; GyrI-like; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00871; AraC_E_bind; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF55136; Probable bacterial effector-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001412}.
FT DOMAIN 5..75
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT COILED 82..116
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 275 AA; 33135 MW; 41B775D892645B2E CRC64;
MKHKKYKINE VAKMHNISKK TLIYYDKIGL FKPQYVDEEN NYRYYEMKEL PILKQIVYLK
KIGFSLKEIK NLLDNREHDL VIEALISRDK EIMNAMEELQ EMHNSIEHLL NFYKKTKYID
KKDLYKPSVK IFTKRKVFYL KCEEEVNEDN KEEIMLTYRR ALNYLQQLNL FSHQEYGTIY
LKQGIKEGFS KNVGSFISIP DKYDIKEQTI LKEGKYICMY KNGGYYNEGA VKYLLNWIKE
NGYEAISDIY EYCLIDYTFT KSVEDMISEI QVRVR
//
