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Database: UniProt
Entry: Q89AF9
LinkDB: Q89AF9
Original site: Q89AF9 
ID   DEAD_BUCBP              Reviewed;         602 AA.
AC   Q89AF9;
DT   30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2003, sequence version 1.
DT   16-OCT-2019, entry version 113.
DE   RecName: Full=ATP-dependent RNA helicase DeaD {ECO:0000255|HAMAP-Rule:MF_00964};
DE            EC=3.6.4.13 {ECO:0000255|HAMAP-Rule:MF_00964};
DE   AltName: Full=Cold-shock DEAD box protein A {ECO:0000255|HAMAP-Rule:MF_00964};
GN   Name=deaD {ECO:0000255|HAMAP-Rule:MF_00964};
GN   OrderedLocusNames=bbp_335;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: DEAD-box RNA helicase involved in various cellular
CC       processes at low temperature, including ribosome biogenesis, mRNA
CC       degradation and translation initiation. {ECO:0000255|HAMAP-
CC       Rule:MF_00964}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00964};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00964}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DeaD
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00964}.
DR   EMBL; AE016826; AAO27056.1; -; Genomic_DNA.
DR   RefSeq; WP_011091457.1; NC_004545.1.
DR   SMR; Q89AF9; -.
DR   STRING; 224915.bbp_335; -.
DR   PRIDE; Q89AF9; -.
DR   EnsemblBacteria; AAO27056; AAO27056; bbp_335.
DR   KEGG; bab:bbp_335; -.
DR   eggNOG; ENOG4105C1J; Bacteria.
DR   eggNOG; COG0513; LUCA.
DR   KO; K05592; -.
DR   OMA; LPQGMPK; -.
DR   OrthoDB; 626183at2; -.
DR   BioCyc; BAPH224915:G1G09-338-MONOMER; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0070417; P:cellular response to cold; IEA:InterPro.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd12499; RRM_EcCsdA_like; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   HAMAP; MF_00964; DEAD_helicase_DeaD; 1.
DR   InterPro; IPR034415; CsdA_RRM.
DR   InterPro; IPR005580; DbpA/CsdA_RNA-bd_dom.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR028618; DEAD_helicase_DeaD.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF03880; DbpA; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; RNA-binding; Stress response.
FT   CHAIN         1    602       ATP-dependent RNA helicase DeaD.
FT                                /FTId=PRO_0000055100.
FT   DOMAIN       37    208       Helicase ATP-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00964}.
FT   DOMAIN      231    378       Helicase C-terminal. {ECO:0000255|HAMAP-
FT                                Rule:MF_00964}.
FT   NP_BIND      50     57       ATP. {ECO:0000255|HAMAP-Rule:MF_00964}.
FT   MOTIF         6     34       Q motif.
FT   MOTIF       156    159       DEAD box.
SQ   SEQUENCE   602 AA;  68490 MW;  F1508E82CBB4D69B CRC64;
     MTHTNMTFSS FGLNSCIITA LNDIGYVQPS PIQAACIPYL IKGKDVLGMA QTGSGKTAAF
     ALPLLHNIKL DVRVPQILVL TPTRELAVQV AEAFSNFSKK LIGVHVLALY GGQRYDLQLK
     SLRKGPQIIV GTPGRLLDHL KRRTLSLSNL HSLVLDEADE MLRMGFIEDV ETIMTEIPDR
     HQTALFSATM PEAIRRISRR FMKNPKEIRI QSNITTRPDI QQSYWMVYGK KTDALIRFLE
     AEDFSATIIF VRTKNATLEV SEVLERYGYN SAALNGDMNQ SLREQTLEKL KDGRLDILIA
     TDVAARGLDV DRISFVINYD IPMDSESYVH RIGRTGRAGR KGKALLFVEN RERRLLRNIE
     RAMNISISEV NLPKSDFLSK RRLEKFAQKV QIQLDSKDLH EYRGLLPKLQ PNNNSLDIES
     LAAALLKMAQ GERSLIVKPE SIVRARHLKI KDTYRNNNYK SLNYVSRYNR DKNVDLYRID
     VGRNDGVEVR HIVGAIANEG DISSRKIGNV RLFSNYSTIE LPKGLSNTLP KTFIRTKILN
     KFINIKLLYN SNFKGNYNDI KDVKVYNSNK LRSKKMNNKK FVSSGVRKKI KTNISCNRRR
     SV
//
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