ID Q89LT6_BRADU Unreviewed; 1049 AA.
AC Q89LT6;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:BAC49722.1};
GN OrderedLocusNames=blr4457 {ECO:0000313|EMBL:BAC49722.1};
OS Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS NBRC 14792 / USDA 110).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC49722.1, ECO:0000313|Proteomes:UP000002526};
RN [1] {ECO:0000313|Proteomes:UP000002526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC {ECO:0000313|Proteomes:UP000002526};
RX PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
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DR EMBL; BA000040; BAC49722.1; -; Genomic_DNA.
DR RefSeq; NP_771097.1; NC_004463.1.
DR RefSeq; WP_011087229.1; NZ_CP011360.1.
DR AlphaFoldDB; Q89LT6; -.
DR STRING; 224911.AAV28_19440; -.
DR EnsemblBacteria; BAC49722; BAC49722; BAC49722.
DR GeneID; 64024201; -.
DR KEGG; bja:blr4457; -.
DR PATRIC; fig|224911.44.peg.4227; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_5; -.
DR InParanoid; Q89LT6; -.
DR OrthoDB; 9807350at2; -.
DR PhylomeDB; Q89LT6; -.
DR Proteomes; UP000002526; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF21; MULTIDRUG RESISTANCE PROTEIN MDTB; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002526};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 866..883
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 961..982
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 994..1020
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1049 AA; 111258 MW; EAD54303C261DEF2 CRC64;
MGVSEPFIRR PIATSLLGIA LLIGGLLGYF SLPVSALPQV DFPTVQVTTQ LPGASPDVIA
SLITAPLERQ LGQIPSLSAM NSTSSFGVSQ ISLQFDLNRD IDGATQDVQA AINAAAGVLP
KTLPYPPTYA KVNPADAPVM TLALRSDTIS LRAMSDIADT LLAQRLSQIS GVGRVSVLGG
LKPAVRIQAD LARLAAYGIA MEDLRTAIAN ANVSGPKGSL DGAQQSYIIA ANDQIAAAEA
YKPVIIAYRN GSPVTIADVA QIVDGLENDR TGGWYQGTPA VIIDIQRQPG ANVIDVVSQI
RAEIPKVQRA IPAGVNLTIV SDRTVTIRAS VRDVQFTLIL SVVLVTLVVL LFLRSLRATL
IAGVALPLSL IASFGIMYFA GFSLDNLSLM ALTIGTGFVV DDAIVMIENI VRHMENGDGP
MEASLKGASE IGFTVISLTV SLIAVFIPLL FMSGLVGRMF REFALTLTIA VVTSAVVSLT
LTPMMCSRLL RHAHEEVAVP GLAAISRFID RTVEFYHRTL LWVLERQRAT LVVTFATLIA
TLVLYVVAPK GFLPLQDTAS ITAVTEAGPD VSFAEMQRRQ AEAADAIKAD PDVVGVVSVI
GAGSVNPTTN VGRLVMTLKP RGERRDDVSV VVTRLKQRVS GIPGMTVYFQ PVQDVQISTQ
SSRSQYQYTL TGTDAALVSE WARKLVAEMR RDPLFRDVSS EAQEGGLRAQ LDVDRTRAGQ
LGVSLQGITD TLNDAFAQRQ ISTIYGQANQ YRVVLEALPM YQRDPSILSK LYLPGAASAI
VGAPNAQVPL SAVATLKRTT APLAISHQAQ FPAISLSFNL APGAALGDAV EAVKTIETRI
EMPNSIVGVY AGDAAEFAKA LAGQPWLLLA AVITIYIVLG VLYESYIHPI TILSTLPSAG
VGAILALVLC GQDLSVIGLI GIILLMGIVK KNAIMMIDFA LEAERGQGMS PNEAIVQACL
LRFRPIMMTT LAALFGALPL AIESGTGAEL RFPLGISIIG GLLLSQLLTL YTTPVIYLAL
DRINRRLEQA LPPAESGGPP VAGATEGMQ
//
