ID Q89LX0_BRADU Unreviewed; 308 AA.
AC Q89LX0;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Bll4423 protein {ECO:0000313|EMBL:BAC49688.1};
GN OrderedLocusNames=bll4423 {ECO:0000313|EMBL:BAC49688.1};
OS Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS NBRC 14792 / USDA 110).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC49688.1, ECO:0000313|Proteomes:UP000002526};
RN [1] {ECO:0000313|Proteomes:UP000002526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC {ECO:0000313|Proteomes:UP000002526};
RX PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; BA000040; BAC49688.1; -; Genomic_DNA.
DR RefSeq; NP_771063.1; NC_004463.1.
DR RefSeq; WP_011087195.1; NZ_CP011360.1.
DR AlphaFoldDB; Q89LX0; -.
DR STRING; 224911.AAV28_19260; -.
DR EnsemblBacteria; BAC49688; BAC49688; BAC49688.
DR GeneID; 64024167; -.
DR KEGG; bja:bll4423; -.
DR PATRIC; fig|224911.44.peg.4188; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_049343_5_0_5; -.
DR InParanoid; Q89LX0; -.
DR OrthoDB; 9778880at2; -.
DR PhylomeDB; Q89LX0; -.
DR Proteomes; UP000002526; Chromosome.
DR GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IBA:GO_Central.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000002526}.
FT ACT_SITE 138
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 166
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 208
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 308 AA; 33441 MW; 5973418D298B208B CRC64;
MSRRVSWEGV FPAVTTQFHD DLSLDIDATA KVMDGLIRDG VSGLIVCGSV GENTSLERKE
KVAIMETAKS VAAGRVPVLC GIAEFTTAFA VETAKEAARV GIDGVMVMPA LVYSSKPHET
AAHFRAVATA TDLPVMLYNN PPIYKNDVTP DILASLADVE TVVSFKDSSG DTRRFIDTRN
MVGDRFVLFA GLDDVIVESV AMGAVGWVSG MSNAFPREGE TLFRLAKAGR YAEAMPLYEW
FMPLLHLDAR PDLVQCIKLC EHIMGRGTVL TRPPRLALLP QEKAEVEAMM VKALKSRPRL
PDVGLKAA
//
