ID Q89Z90_BACTN Unreviewed; 333 AA.
AC Q89Z90;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Membrane-bound lytic murein transglycosylase {ECO:0000313|EMBL:AAO79592.1};
GN OrderedLocusNames=BT_4487 {ECO:0000313|EMBL:AAO79592.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO79592.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO79592.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO79592.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC -!- SIMILARITY: Belongs to the transglycosylase Slt family.
CC {ECO:0000256|ARBA:ARBA00007734}.
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DR EMBL; AE015928; AAO79592.1; -; Genomic_DNA.
DR RefSeq; NP_813398.1; NC_004663.1.
DR AlphaFoldDB; Q89Z90; -.
DR STRING; 226186.BT_4487; -.
DR CAZy; GH23; Glycoside Hydrolase Family 23.
DR PaxDb; 226186-BT_4487; -.
DR EnsemblBacteria; AAO79592; AAO79592; BT_4487.
DR KEGG; bth:BT_4487; -.
DR PATRIC; fig|226186.12.peg.4569; -.
DR eggNOG; COG0741; Bacteria.
DR HOGENOM; CLU_009520_1_1_10; -.
DR InParanoid; Q89Z90; -.
DR OrthoDB; 9815002at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008932; F:lytic endotransglycosylase activity; IBA:GO_Central.
DR CDD; cd16894; MltD-like; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR PANTHER; PTHR37423:SF2; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE; 1.
DR PANTHER; PTHR37423; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED; 1.
DR Pfam; PF01464; SLT; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001414};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..211
FT /note="Transglycosylase SLT"
FT /evidence="ECO:0000259|Pfam:PF01464"
SQ SEQUENCE 333 AA; 38577 MW; 0DA655E5E19B4891 CRC64;
MTKRKQKMKK FTKINYILTF ILVFCIGATL PILIGSSHVD EQHSAKSEVP YCVTSPTVPE
QVTFDGETID LRRYDRRERM DREMMAFTYM HSTTMLLIKR ANRYFPIIEP ILKANGIPDD
FKYLMVIESN LNNIARSPAG AAGLWQFMPA TGREFGLEVN ENVDERYHIE KATVAACKYF
KQAYAKYGDW MAVSAAYNAG QGRISSQLDQ QLASHAMDLW LVEETSRYMF RLLAVKEIFK
NPQRYGFLLK KEHLYPPIPY KEITVTTPIA NLSDFAKQQG ITYAQLRDAN PWLREQTLKN
RTGKTYVLQI PTQEGMYYDP KKTVAYNKHW VID
//
