ID Q8A3W7_BACTN Unreviewed; 336 AA.
AC Q8A3W7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=2-oxoglutarate synthase subunit korB {ECO:0000313|EMBL:AAO77943.1};
GN OrderedLocusNames=BT_2837 {ECO:0000313|EMBL:AAO77943.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO77943.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO77943.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO77943.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO77943.1; -; Genomic_DNA.
DR RefSeq; NP_811749.1; NC_004663.1.
DR RefSeq; WP_011108506.1; NC_004663.1.
DR AlphaFoldDB; Q8A3W7; -.
DR STRING; 226186.BT_2837; -.
DR PaxDb; 226186-BT_2837; -.
DR DNASU; 1071923; -.
DR EnsemblBacteria; AAO77943; AAO77943; BT_2837.
DR GeneID; 60924019; -.
DR KEGG; bth:BT_2837; -.
DR PATRIC; fig|226186.12.peg.2884; -.
DR eggNOG; COG1013; Bacteria.
DR HOGENOM; CLU_048564_1_0_10; -.
DR InParanoid; Q8A3W7; -.
DR OrthoDB; 9775140at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd03375; TPP_OGFOR; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001414}.
FT DOMAIN 51..198
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 336 AA; 36583 MW; ABF3AB1C64E50599 CRC64;
MSDKVYTVQD YKSGQPRWCP GCGDHAFLNS LHKAMAELGV APHNIAVISG IGCSSRLPYY
VNTYGFHTIH GRAAAVATGA KVANPDLTIW QISGDGDGLA IGGNHFIHAV RRNIDLNMIL
LNNRIYGLTK GQYSPTSERG FVSKSSPYGT VEDPFHPAEL AFGARGRFFA RCIAVDGAAS
VEVLKAAANH KGASVVEVLQ NCVIFNDGTH ASVATKEGRA KNAIYLEHGK PMLFGENKEF
GLMQEGFGLK VVKLGENGIT EKDILIHDAH CQDNTLQLKL ALMEGPDFPI ALGVIREVEA
PTYNDAVAEQ IEEVKGKKKY HNFQELLMTN DTWEVK
//
