ID Q8A688_BACTN Unreviewed; 797 AA.
AC Q8A688;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:AAO77105.1};
GN OrderedLocusNames=BT_1998 {ECO:0000313|EMBL:AAO77105.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO77105.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO77105.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO77105.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO77105.1; -; Genomic_DNA.
DR RefSeq; NP_810911.1; NC_004663.1.
DR RefSeq; WP_008766366.1; NC_004663.1.
DR AlphaFoldDB; Q8A688; -.
DR STRING; 226186.BT_1998; -.
DR PaxDb; 226186-BT_1998; -.
DR EnsemblBacteria; AAO77105; AAO77105; BT_1998.
DR GeneID; 60927983; -.
DR KEGG; bth:BT_1998; -.
DR PATRIC; fig|226186.12.peg.2049; -.
DR eggNOG; COG1328; Bacteria.
DR HOGENOM; CLU_002707_2_1_10; -.
DR InParanoid; Q8A688; -.
DR OrthoDB; 9804622at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0031250; C:anaerobic ribonucleoside-triphosphate reductase complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IBA:GO_Central.
DR GO; GO:0009265; P:2'-deoxyribonucleotide biosynthetic process; IBA:GO_Central.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01675; RNR_III; 1.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000001414}.
FT DOMAIN 6..94
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
SQ SEQUENCE 797 AA; 90311 MW; F4D824A8A8C7550A CRC64;
MNYAEICIIK RDGKREDFSI SKIKNAIGKA FSATGIQNEQ QLIADVTMSV ISQFTNPTIT
VEEIQDLVEK ALMKVRPEVA KKYIIYREWR NTERDKKTQM KHVMDGIVAI DKNDVNLSNA
NMSSHTPAGQ MMTFASEVTK DYTYKYLLPK RFAEAHQLGD VHIHDLDYYP TKTTTCIQYD
MDDLFERGFR TKNGSIRTPQ SIQSYATLAT IIFQTNQNEQ HGGQAIPAFD FFMAKGVAKS
FRKHLASFIN FYVAMENGTQ ADEKAIRTLI KEHLPSIKST EAERETLRIA LIALQIIIDK
EHLTRIAEKA YQQTKKDTHQ AMEGFIHNLN TMHSRGGNQV VFSSINYGTD TSAEGRLVIE
ELLKATIEGL GTRGEVPVFP IQIFKVKDGV SYSEKDFEKA MKAENIEDAM RGTYEAPNFD
LLLRACQTTS KALFPNFMFL DTPFNKNEKW KADDPKRYIY ELATMGCRTR VFENVAGEKS
SLGRGNLSFT TLNMPRLAIE ARIKAENLIE GERNKDAIEQ KAKEIFMESV RNMATLVADQ
LYERYQYQRT ALARQFPFMM GNDVWKGGGA LNPNEQVGDA LRSGTLGIGF IGGHNAMVAL
YGEGHGHSQK AWDTLYEAVM EMNKVVDEYK EKYNLNYSVL ATPAEGLSGR FTKIDRRKYG
KIPGVTDRDY YVNSFHVDVK EPISITEKIR CEAPFHAITR GGHITYVELD GEAQKNVRAI
AKIVKVMHDE GIGYGSINHP VDTCHNCGYK GVIFDKCPVC QSENILRMRR ITGYLTGDLS
SWNSAKRAEE KDRVKHL
//
