ID Q8A8E9_BACTN Unreviewed; 232 AA.
AC Q8A8E9;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=Abasic site processing protein {ECO:0000256|RuleBase:RU364100};
DE EC=3.4.-.- {ECO:0000256|RuleBase:RU364100};
GN OrderedLocusNames=BT_1218 {ECO:0000313|EMBL:AAO76325.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO76325.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO76325.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0007829|PDB:2F20}
RP X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
RA Vorobiev S.M., Abashidze M., Seetharaman J., Forouhar F., Xiao R.,
RA Ma L.-C., Montelione G.T., Tong L., Hunt J.F.;
RT "Crystal structure of the Q8A8E9_BACTIN hypothetical protein from
RT Bacteroides thetaiotaomicron.";
RL Submitted (NOV-2005) to the PDB data bank.
RN [3] {ECO:0000313|EMBL:AAO76325.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC -!- SIMILARITY: Belongs to the SOS response-associated peptidase family.
CC {ECO:0000256|ARBA:ARBA00008136, ECO:0000256|RuleBase:RU364100}.
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DR EMBL; AE015928; AAO76325.1; -; Genomic_DNA.
DR RefSeq; NP_810131.1; NC_004663.1.
DR RefSeq; WP_008765986.1; NZ_UYXG01000007.1.
DR PDB; 2F20; X-ray; 2.10 A; A/B=1-232.
DR PDBsum; 2F20; -.
DR AlphaFoldDB; Q8A8E9; -.
DR SMR; Q8A8E9; -.
DR PaxDb; 226186-BT_1218; -.
DR EnsemblBacteria; AAO76325; AAO76325; BT_1218.
DR GeneID; 60927195; -.
DR KEGG; bth:BT_1218; -.
DR PATRIC; fig|226186.12.peg.1242; -.
DR eggNOG; COG2135; Bacteria.
DR HOGENOM; CLU_035990_6_4_10; -.
DR InParanoid; Q8A8E9; -.
DR OrthoDB; 9782620at2; -.
DR EvolutionaryTrace; Q8A8E9; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1680.10; SOS response associated peptidase-like; 1.
DR InterPro; IPR003738; SRAP.
DR InterPro; IPR036590; SRAP-like.
DR PANTHER; PTHR13604:SF0; ABASIC SITE PROCESSING PROTEIN HMCES; 1.
DR PANTHER; PTHR13604; DC12-RELATED; 1.
DR Pfam; PF02586; SRAP; 1.
DR SUPFAM; SSF143081; BB1717-like; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2F20};
KW Covalent protein-DNA linkage {ECO:0000256|ARBA:ARBA00023124};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364100};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU364100};
KW Reference proteome {ECO:0000313|Proteomes:UP000001414}.
SQ SEQUENCE 232 AA; 27129 MW; BBA4C42F18469C8E CRC64;
MCFHNSMSAK AIKVAARYGR QSDVVEIYQS ILDEQYHVNA FTFPRYPIIT SSDEVQVFNW
GLIPFWVRSE EDATEIRKMT LNARADTIFE KPSFREPIMK KRCIVPSTGY FEWRHEGANK
IPYYIYVKDE PIFSMAGIYD RWLDKDTGEE HETFSIITTD TNSLTDYIDN TKHRMPAILT
QEEEEKWLNP SLSKAEIASL LKPFDTEKMD AYVIRNDFLK KSPNDPTIVQ RA
//
