ID Q8A9J3_BACTN Unreviewed; 267 AA.
AC Q8A9J3;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Metallo-beta-lactamase superfamily hydrolase {ECO:0000313|EMBL:AAO75929.1};
GN OrderedLocusNames=BT_0822 {ECO:0000313|EMBL:AAO75929.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO75929.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO75929.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO75929.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO75929.1; -; Genomic_DNA.
DR RefSeq; NP_809735.1; NC_004663.1.
DR RefSeq; WP_008761509.1; NZ_UYXG01000002.1.
DR AlphaFoldDB; Q8A9J3; -.
DR STRING; 226186.BT_0822; -.
DR PaxDb; 226186-BT_0822; -.
DR DNASU; 1073244; -.
DR EnsemblBacteria; AAO75929; AAO75929; BT_0822.
DR GeneID; 60926790; -.
DR KEGG; bth:BT_0822; -.
DR PATRIC; fig|226186.12.peg.838; -.
DR eggNOG; COG1235; Bacteria.
DR HOGENOM; CLU_073253_0_0_10; -.
DR InParanoid; Q8A9J3; -.
DR OrthoDB; 9781189at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd07733; YycJ-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR47619; METALLO-HYDROLASE YYCJ-RELATED; 1.
DR PANTHER; PTHR47619:SF1; METALLO-HYDROLASE YYCJ-RELATED; 1.
DR Pfam; PF12706; Lactamase_B_2; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAO75929.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001414}.
FT DOMAIN 13..195
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 267 AA; 30434 MW; 4052DAD0A4146DC9 CRC64;
MKVRFISLAS GSSGNCYYLG TDTYGILIDA GIGIRTIKKT LKDFNILMES IRAVFVTHDH
ADHIKAVGHL GEKMNIPVYT TARIHEGINR SYCMTEKLST SVRYLEKQVP MMLEDFRIES
FEVPHDGTDN VGYCIEIDGK VFSFLTDLGE ITPTAADYIS KANYLILEAN YDEEMLKMGP
YPQYLKERIM SRTGHMSNSA TAEFLAENIT EHLRYIWLCH LSKDNNHPEL AYKTVEWKLK
NKGVIVGKDV QLLALKRNTP SELYVFE
//
