ID Q8CJS0_STRCO Unreviewed; 491 AA.
AC Q8CJS0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:CAD55345.1};
GN OrderedLocusNames=SCO5239 {ECO:0000313|EMBL:CAD55345.1};
GN ORFNames=2SC7G11.01 {ECO:0000313|EMBL:CAD55345.1}, SC7E4.36
GN {ECO:0000313|EMBL:CAD55345.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAD55345.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAD55345.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
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DR EMBL; AL939123; CAD55345.1; -; Genomic_DNA.
DR RefSeq; NP_733658.1; NC_003888.3.
DR RefSeq; WP_003973732.1; NZ_VNID01000008.1.
DR AlphaFoldDB; Q8CJS0; -.
DR STRING; 100226.gene:17762890; -.
DR PaxDb; 100226-SCO5239; -.
DR PATRIC; fig|100226.15.peg.5323; -.
DR eggNOG; COG3920; Bacteria.
DR HOGENOM; CLU_045351_1_0_11; -.
DR InParanoid; Q8CJS0; -.
DR OrthoDB; 9767435at2; -.
DR PhylomeDB; Q8CJS0; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd16951; HATPase_EL346-LOV-HK-like; 1.
DR Gene3D; 3.30.450.280; GAF domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR022066; PdtaS_GAF.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12282; PdtaS_GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CAD55345.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Transferase {ECO:0000313|EMBL:CAD55345.1}.
FT DOMAIN 293..489
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 491 AA; 54176 MW; 66F8A92C890A3107 CRC64;
MPSMNELVRQ HTALDDSDLE WLHLLVSEWQ LLSDLSFADL VLWVPTRDGT RYVSVAQMRP
NTGPTSYQDD MVGHLVPRGR RPMLDAALDE GRIVREGDPE WREEVPVRVE SIPVRRQGRV
LGVIARNTNL LTVRTPSRLE LTYLQSASDL AQMIAAGAFP FENQQVDMDA SPRVGDGLIR
VDGDGIVQYA SPNALSAYHR MGLAADLVGH HLGRTTAELA PSRGPVDEAL AKVASGWAPR
EFEIEAHDGV IQFRAIPLKP KGTRIGSLVL LRDVTELRRR ERELITKDAT IREIHHRVKN
NLQTVAALLR LQARRIESDR GREALEEAVR RVGSIAIVHE TLSQNLDERV EFDEIADRVL
AMVAEISPGK VTGRRTGRFG ILDAEVATPL SMVLTEVLQN ALEHGFRDGD TGTVEVSAVR
GGTTKEARLL VTVQDDGVGL PEDFDPHRSG NLGLQIVRTL VEGELGGAFD MVQAAERGCR
VILDIPVPAE K
//
