ID Q8DQZ4_STRR6 Unreviewed; 407 AA.
AC Q8DQZ4;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Xylose repressor protein {ECO:0000313|EMBL:AAK99224.1};
GN Name=xylR {ECO:0000313|EMBL:AAK99224.1};
GN OrderedLocusNames=spr0420 {ECO:0000313|EMBL:AAK99224.1};
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101 {ECO:0000313|EMBL:AAK99224.1, ECO:0000313|Proteomes:UP000000586};
RN [1] {ECO:0000313|EMBL:AAK99224.1, ECO:0000313|Proteomes:UP000000586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6 {ECO:0000313|Proteomes:UP000000586};
RX PubMed=11544234; DOI=10.1128/JB.183.19.5709-5717.2001;
RA Hoskins J.A., Alborn W.Jr., Arnold J., Blaszczak L., Burgett S.,
RA DeHoff B.S., Estrem S., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A., LaGace R., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S., McHenney M.,
RA McLeaster K., Mundy C., Nicas T.I., Norris F.H., O'Gara M., Peery R.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C., Baltz R.H., Jaskunas S.Richard.,
RA Rosteck P.R.Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; AE007317; AAK99224.1; -; Genomic_DNA.
DR PIR; D97924; D97924.
DR RefSeq; NP_358014.1; NC_003098.1.
DR RefSeq; WP_000628991.1; NC_003098.1.
DR AlphaFoldDB; Q8DQZ4; -.
DR SMR; Q8DQZ4; -.
DR STRING; 171101.spr0420; -.
DR KEGG; spr:spr0420; -.
DR PATRIC; fig|171101.6.peg.462; -.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_1_9; -.
DR Proteomes; UP000000586; Chromosome.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000586}.
SQ SEQUENCE 407 AA; 45694 MW; 8E2741EBAADF1043 CRC64;
MITKQSAFLQ NRATILEFLY RNPATSRTDI VNETGLTPAT TTNIIKELSE QSLIYETGDE
FSEFSGSGRR RKTISITDNI PYVVGGIEIN VLGIFLSLCD LQGKTLFETE ILNEDYPISE
INSTITNMIK TAIEYVPLET KLLGFGLSIP GHYNKDSGSI ITNNPIWESF NLLNVIKDFN
FPFIVKNNID CMAIGQYLFN PHNTPDNFIF LHAGLGIYTS FFTKEKIGAS KNPYIGEIGH
TIVELNGQYC ECGKKGCLQT YISDAWLIKH AQLLFKNSQL TVLKSLVKTE KDIHLDTLLT
AYNLGDSALR QQIDKGVNLL ATSIANLLLI NPADKIYINS QLLNYQPFTH EVRDKIQDQL
HFVPFTRNIE IEILPYNKHR GSIGACALAI VAFFIEHSNV LQDIISP
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