ID Q8DYW4_STRA5 Unreviewed; 415 AA.
AC Q8DYW4;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Permease, putative {ECO:0000313|EMBL:AAN00230.1};
GN OrderedLocusNames=SAG1359 {ECO:0000313|EMBL:AAN00230.1};
OS Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=208435 {ECO:0000313|EMBL:AAN00230.1, ECO:0000313|Proteomes:UP000000821};
RN [1] {ECO:0000313|EMBL:AAN00230.1, ECO:0000313|Proteomes:UP000000821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-611 / 2603 V/R {ECO:0000313|Proteomes:UP000000821};
RX PubMed=12200547; DOI=10.1073/pnas.182380799;
RA Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.,
RA Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D.,
RA Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA DeBoy R.T., Durkin S., Kolonay J.F., Umayam L.A., Madupu R., Lewis M.R.,
RA Radune D., Fedorova N.B., Scanlan D., Khouri H., Mulligan S., Carty H.A.,
RA Cline R.T., Gill J., Scarselli M., Mora M., Iacobini E.T., Brettoni C.,
RA Galli G., Mariani M., Vegni F., Maione D., Rinaudo D., Rappuoli R.,
RA Telford J.L., Kasper D.L., Grandi G., Fraser C.M.;
RT "Complete genome sequence and comparative genomic analysis of an emerging
RT human pathogen, serotype V Streptococcus agalactiae.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC {ECO:0000256|ARBA:ARBA00038076}.
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DR EMBL; AE009948; AAN00230.1; -; Genomic_DNA.
DR RefSeq; NP_688357.1; NC_004116.1.
DR RefSeq; WP_000432854.1; NC_004116.1.
DR AlphaFoldDB; Q8DYW4; -.
DR STRING; 208435.SAG1359; -.
DR GeneID; 66886225; -.
DR KEGG; sag:SAG1359; -.
DR PATRIC; fig|208435.3.peg.1367; -.
DR HOGENOM; CLU_000604_8_0_9; -.
DR OrthoDB; 9770036at2; -.
DR Proteomes; UP000000821; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR025857; MacB_PCD.
DR PANTHER; PTHR30572:SF4; MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB; 1.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR Pfam; PF02687; FtsX; 1.
DR Pfam; PF12704; MacB_PCD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000821};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..254
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 294..408
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
SQ SEQUENCE 415 AA; 45406 MW; B0DDE93062087CCA CRC64;
MENWKFALSS ILGHKMRAFL TMLGIIIGVA SVVLIMALGK GMKDSVTNEI TKSQKNLQIY
YKTKEDQKNE DNFGAQGAFM QGSDTNRKEP IIQESWLKKI AKEVDGVSGY YVTNQTNAPV
AYLEKKAKTV NITGINRTYL GIKKFKIKSG RQFQEEDYNQ FSRVILLEEK LAQRLFQTNE
AALNKVVTVK NKSYLVVGVY SDPEAGSGLY GSNSDGNAIL TNTQLASEFG AKEAENIYFH
LNDVSQSNRI GKEIGKRLTD ISHAKDGYYD NFDMTSIVKS INTQVGIMTG VIGAIAAISL
LVGGIGVMNI MLVSVTERTR EIGLRKALGA TRRKILAQFL IESMVLTILG GLIGLLLAYG
GTMLIANAQD KITPSVSLNV AIGSLIFSAF IGIIFGLLPA NKASKLNPID ALRYE
//
