ID Q8E936_SHEON Unreviewed; 485 AA.
AC Q8E936;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN OrderedLocusNames=SO_4457 {ECO:0000313|EMBL:AAN57422.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN57422.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN57422.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN57422.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE014299; AAN57422.1; -; Genomic_DNA.
DR RefSeq; NP_719978.1; NC_004347.2.
DR RefSeq; WP_011074089.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8E936; -.
DR STRING; 211586.SO_4457; -.
DR PaxDb; 211586-SO_4457; -.
DR KEGG; son:SO_4457; -.
DR PATRIC; fig|211586.12.peg.4318; -.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_029518_0_0_6; -.
DR OrthoDB; 5496380at2; -.
DR PhylomeDB; Q8E936; -.
DR BioCyc; SONE211586:G1GMP-4117-MONOMER; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0052621; F:diguanylate cyclase activity; IBA:GO_Central.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IBA:GO_Central.
DR GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AAN57422.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186};
KW Transferase {ECO:0000313|EMBL:AAN57422.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 354..485
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 485 AA; 55548 MW; D83C1298FDC2DFB3 CRC64;
MGNHVWNDKK KFIWLLSVLL LVAFLVTSGI SYKVAHDSLS QQIESNTLPL TSDNIYSEIQ
QDLLRPIFIS SLMAQDTFVR DWTLNHEQEP EKLIRYLKEI QDKYDTVTSF FISEQSRNYY
HSSGVLKKIQ DVEPNDAWYF RVRSLPESEH YEINIDADTA DRTKTTVFVN YKVFDFESKF
IGVTGVGLAV EKVKALIELY QKRYNRRVFF TDRQGNVTLH GDEYDGANSL QASTGLEQLA
TRILTSPSAA FSYQRNGKTV YLNSRLVPEF KWYLVVEQED APQEQELLNT FWGNLALSLV
VTIGILFISN MTLGRYQRKL EIMASTDKLT GAANRQVFEE YFHQALDKAK LSQTSISILL
IDIDHFKKVN DSYGHSVGDL VLKTVTNLLR SQLKPQDILC RWGGEEFLVL LPEMDLSRAA
ELAERFRDSI SQRELKVNGV HIAITVSIGV AEYQKLEPAE DLIKRADLAL YQAKEAGRNQ
VVLNQ
//
