ID Q8EB46_SHEON Unreviewed; 555 AA.
AC Q8EB46;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 140.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=SO_3688 {ECO:0000313|EMBL:AAN56673.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN56673.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN56673.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN56673.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; AE014299; AAN56673.1; -; Genomic_DNA.
DR RefSeq; NP_719229.1; NC_004347.2.
DR RefSeq; WP_011073483.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8EB46; -.
DR STRING; 211586.SO_3688; -.
DR PaxDb; 211586-SO_3688; -.
DR KEGG; son:SO_3688; -.
DR PATRIC; fig|211586.12.peg.3574; -.
DR eggNOG; COG5000; Bacteria.
DR HOGENOM; CLU_000445_114_4_6; -.
DR OrthoDB; 1931120at2; -.
DR PhylomeDB; Q8EB46; -.
DR BioCyc; SONE211586:G1GMP-3432-MONOMER; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF51; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13188; PAS_8; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AAN56673.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AAN56673.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 177..229
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 353..555
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 555 AA; 62668 MW; ADBB4D30338BBD29 CRC64;
MQLRTKLVIY STVCCAFGVL LTLATMKYLF STSSPEVATP ATLPDVQLPE LDLAQLQDSV
AAIESAIKNT EQFQQAFSLQ ERLRADQIKH ELQKLEQLKQ EQLQIKLYKL ELLKQGLFNP
APHPANMVPA LPVVEQSKLP PLSLDPQAEH TPPIFELVLV ILLACSVCAL GVAWFTRHLA
RSLDALEVGL LNFNDNDFSV SIPTNGEGQL KTLAELFNHS AAKLRQERQY IYQRELLLDK
VIQSSPNVML LLNDHQRLMY ANDAARHLFQ IKGKMEGLSL EELLQELPEA LALALKQEKS
GLFTMGEDDA ETWYLSRGQF LLNNQQHNLI LLKQMTRELN RQEVAVWKKV IRIISHELNN
SVAPIASMVN SGRLLTKDLD NPKLKLIFDT IESRTNHLSQ FIYNYARFAK LPLPQRRKVA
WSQLIEQLTQ HYPFSLTHEL PIEDGYVDQG QMEQVLLNLL KNAHESGSNP EEVTLSIRYQ
KMVDGGGFSI KIEDRGSGMS EEVLEQALLP FYSTKQSGTG LGLPLCREII EAHDGSISMH
NRTEGGLSVL LWLPQ
//
