ID Q8EJX0_SHEON Unreviewed; 507 AA.
AC Q8EJX0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Sodium:proton antiporter NhaC family {ECO:0000313|EMBL:AAN53421.1};
GN OrderedLocusNames=SO_0336 {ECO:0000313|EMBL:AAN53421.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN53421.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN53421.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN53421.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE014299; AAN53421.1; -; Genomic_DNA.
DR RefSeq; NP_715976.1; NC_004347.2.
DR RefSeq; WP_011070701.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8EJX0; -.
DR STRING; 211586.SO_0336; -.
DR PaxDb; 211586-SO_0336; -.
DR KEGG; son:SO_0336; -.
DR PATRIC; fig|211586.12.peg.326; -.
DR eggNOG; COG1757; Bacteria.
DR HOGENOM; CLU_018751_1_0_6; -.
DR OrthoDB; 9762978at2; -.
DR PhylomeDB; Q8EJX0; -.
DR BioCyc; SONE211586:G1GMP-321-MONOMER; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478:SF3; LYSINE TRANSPORTER LYSW; 1.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 161..468
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 507 AA; 54163 MW; C3B57FDD99245FF7 CRC64;
MLSNLLAILP LFLTLVLALW LRRTLVALGV GILSGALIIA HFDIVQSVSY LLEIGVKQFY
SQDAWQWWHL NVLTAMLLLG SMTQLLARSG AVGLFGDWLY RRIRTGRQAR VGVVLLGWLV
FIDGIFSCLA VGHVCQPLSQ RYGIRQEQLA YLVDSNASPL CSLLPFSSWG PYVMALLAGL
SFLPVSALEA FIEVALSNFY AITTLGLSLI VAWFGVGFRP IESAVLMAAE PSKVTQMDIA
PPSSQGNPWL LAIPMLTLLC ASVGLTLWSG AQQVPAWDIS AWLASADIGA AMRDACLLST
LVTLGLLIMS GRSIGKLLGD LAHGVRMIAF AIAILLCTWM IGAVIQDLGV ASLLADWAKW
YLSPSLLVAG MFLLCAIMAF ATGSSWGTFA IMIPIGGEIA HNMDASLLLP VLSAVMAGSV
FGDHCSPISD TSVLSATSSG CLPHDHVVTQ LPFALIAAFA ALVGFQLVNL SVATVFVWLG
VIGTSLGLLV LMARFYPPWV AARSQTN
//
