ID Q8EKI3_SHEON Unreviewed; 447 AA.
AC Q8EKI3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Zn-dependent protease with chaperone function {ECO:0000313|EMBL:AAN53197.1};
GN OrderedLocusNames=SO_0110 {ECO:0000313|EMBL:AAN53197.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN53197.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN53197.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN53197.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the N-Me-Phe pilin family.
CC {ECO:0000256|ARBA:ARBA00005233}.
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DR EMBL; AE014299; AAN53197.1; -; Genomic_DNA.
DR RefSeq; NP_715752.1; NC_004347.2.
DR RefSeq; WP_011070518.1; NZ_CP053946.1.
DR AlphaFoldDB; Q8EKI3; -.
DR STRING; 211586.SO_0110; -.
DR PaxDb; 211586-SO_0110; -.
DR KEGG; son:SO_0110; -.
DR PATRIC; fig|211586.12.peg.109; -.
DR eggNOG; COG0501; Bacteria.
DR HOGENOM; CLU_053281_0_0_6; -.
DR OrthoDB; 9810445at2; -.
DR BioCyc; SONE211586:G1GMP-107-MONOMER; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0009289; C:pilus; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07325; M48_Ste24p_like; 1.
DR Gene3D; 3.30.700.10; Glycoprotein, Type 4 Pilin; 1.
DR Gene3D; 3.30.2010.10; Metalloproteases ('zincins'), catalytic domain; 1.
DR InterPro; IPR001915; Peptidase_M48.
DR InterPro; IPR001082; Pilin.
DR InterPro; IPR045584; Pilin-like.
DR PANTHER; PTHR43221; PROTEASE HTPX; 1.
DR PANTHER; PTHR43221:SF1; PROTEASE HTPX; 1.
DR Pfam; PF01435; Peptidase_M48; 1.
DR Pfam; PF00114; Pilin; 1.
DR SUPFAM; SSF54523; Pili subunits; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:AAN53197.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..162
FT /note="Peptidase M48"
FT /evidence="ECO:0000259|Pfam:PF01435"
SQ SEQUENCE 447 AA; 49528 MW; E429640BA766D06B CRC64;
MEQVVNTGND NPIQMADTVY SKEKTLFTIL AIISGLIWAV LIIATKGLAL IYVLMFFIIY
LFTHSAFISY LKGTAVEISP EQFPDLHKQY LACCKRLEIK EAPRAYLLAA DGMLNALATR
FLRRNYIVLF SSIVDALESD KDAINFYIGH ELGHIRRNHI GKEPLLVFAT WLPLIGAAYA
RACEYTCDLH GLRCCNSLRS ATNAVAVLAA GVEQWKRMNV DQYIRQTQES SGFWMSFHEL
NSSYPWLTKR MARVRAKAQG KDYSAPSRSV FAYIISLFTP RMGTAGGGII ILAAIIGVAA
AVAIPAYKEY QEKVGAASIN YDDANNSSST PQMDTEPASV PDAALAIEHI DQLHQSLVPI
TDVLTKYYQN TKGWPTELEV LGLTDEQLST FNLYTDGIVG FVTGEALGDY QGYEVYLSPQ
VDEQDNVTWV CSSNGIPDEY LPADCQG
//
