ID Q8EKM7_SHEON Unreviewed; 177 AA.
AC Q8EKM7;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=Molybdenum cofactor biosynthesis protein MogA {ECO:0000313|EMBL:AAN53152.1};
GN Name=mogA {ECO:0000313|EMBL:AAN53152.1};
GN OrderedLocusNames=SO_0065 {ECO:0000313|EMBL:AAN53152.1};
OS Shewanella oneidensis (strain MR-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=211586 {ECO:0000313|EMBL:AAN53152.1, ECO:0000313|Proteomes:UP000008186};
RN [1] {ECO:0000313|EMBL:AAN53152.1, ECO:0000313|Proteomes:UP000008186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-1 {ECO:0000313|EMBL:AAN53152.1,
RC ECO:0000313|Proteomes:UP000008186};
RX PubMed=12368813; DOI=10.1038/nbt749;
RA Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA Read T.D., Eisen J.A., Seshadri R., Ward N., Methe B., Clayton R.A.,
RA Meyer T., Tsapin A., Scott J., Beanan M., Brinkac L., Daugherty S.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J., Weidman J.,
RA Impraim M., Lee K., Berry K., Lee C., Mueller J., Khouri H., Gill J.,
RA Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C.,
RA Nealson K.H., Fraser C.M.;
RT "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT Shewanella oneidensis.";
RL Nat. Biotechnol. 20:1118-1123(2002).
RN [2] {ECO:0007829|PDB:2F7W, ECO:0007829|PDB:2F7Y}
RP X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS), AND X-RAY CRYSTALLOGRAPHY (1.90
RP ANGSTROMS).
RA Chang C., Mulligan R., Collart F., Joachimiak A.;
RT "Crystal structure of Molybdenum cofactor biosynthesis protein Mog from
RT Shewanella oneidensis.";
RL Submitted (DEC-2005) to the PDB data bank.
RN [3] {ECO:0007829|PDB:3K6A}
RP X-RAY CRYSTALLOGRAPHY (1.89 ANGSTROMS).
RA Chang C., Bigelow L., Joachimiak A.;
RT "Crystal Structure of Molybdenum Cofactor Biosynthesis Protein Mog from
RT Shewanella Oneidensis.";
RL Submitted (OCT-2009) to the PDB data bank.
RN [4] {ECO:0007829|PDB:4NWO}
RP X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH CALCIUM.
RX PubMed=24870237; DOI=10.1038/nature13404;
RA King N.P., Bale J.B., Sheffler W., McNamara D.E., Gonen S., Gonen T.,
RA Yeates T.O., Baker D.;
RT "Accurate design of co-assembling multi-component protein nanomaterials.";
RL Nature 510:103-108(2014).
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE014299; AAN53152.1; -; Genomic_DNA.
DR RefSeq; NP_715707.1; NC_004347.2.
DR RefSeq; WP_011070478.1; NZ_CP053946.1.
DR PDB; 2F7W; X-ray; 1.90 A; A/B/C=1-177.
DR PDB; 2F7Y; X-ray; 2.30 A; A/B/C=1-177.
DR PDB; 3K6A; X-ray; 1.89 A; A/B/C/D/E/F=1-177.
DR PDB; 4NWO; X-ray; 2.80 A; A=1-177.
DR PDBsum; 2F7W; -.
DR PDBsum; 2F7Y; -.
DR PDBsum; 3K6A; -.
DR PDBsum; 4NWO; -.
DR AlphaFoldDB; Q8EKM7; -.
DR SMR; Q8EKM7; -.
DR STRING; 211586.SO_0065; -.
DR PaxDb; 211586-SO_0065; -.
DR KEGG; son:SO_0065; -.
DR PATRIC; fig|211586.12.peg.64; -.
DR eggNOG; COG0521; Bacteria.
DR HOGENOM; CLU_077358_1_0_6; -.
DR OrthoDB; 9784492at2; -.
DR PhylomeDB; Q8EKM7; -.
DR BioCyc; SONE211586:G1GMP-66-MONOMER; -.
DR UniPathway; UPA00344; -.
DR EvolutionaryTrace; Q8EKM7; -.
DR Proteomes; UP000008186; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00886; MogA_MoaB; 1.
DR Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR InterPro; IPR001453; MoaB/Mog_dom.
DR InterPro; IPR008284; MoCF_biosynth_CS.
DR NCBIfam; TIGR00177; molyb_syn; 1.
DR PANTHER; PTHR43764; MOLYBDENUM COFACTOR BIOSYNTHESIS; 1.
DR PANTHER; PTHR43764:SF1; MOLYBDOPTERIN MOLYBDOTRANSFERASE; 1.
DR Pfam; PF00994; MoCF_biosynth; 1.
DR SMART; SM00852; MoCF_biosynth; 1.
DR SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
DR PROSITE; PS01078; MOCF_BIOSYNTHESIS_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2F7W, ECO:0007829|PDB:2F7Y};
KW Calcium {ECO:0007829|PDB:4NWO}; Metal-binding {ECO:0007829|PDB:4NWO};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW Reference proteome {ECO:0000313|Proteomes:UP000008186}.
FT DOMAIN 7..153
FT /note="MoaB/Mog"
FT /evidence="ECO:0000259|SMART:SM00852"
FT BINDING 66
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0007829|PDB:4NWO"
FT BINDING 126
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0007829|PDB:4NWO"
SQ SEQUENCE 177 AA; 19328 MW; 8F8A6C5782AD4784 CRC64;
MSKAKIGIVT VSDRASAGIY EDISGKAIID TLNDYLTSEW EPIYQVIPDE QDVIETTLIK
MADEQDCCLI VTTGGTGPAK RDVTPEATEA VCDRMMPGFG ELMRAESLKF VPTAILSRQT
AGLRGDSLIV NLPGKPKSIR ECLDAVFPAI PYCIDLMEGP YLECNEAVIK PFRPKAK
//
