ID Q8F5R1_LEPIN Unreviewed; 330 AA.
AC Q8F5R1;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:AAN48805.1};
GN Name=wcaG {ECO:0000313|EMBL:AAN48805.1};
GN OrderedLocusNames=LA_1606 {ECO:0000313|EMBL:AAN48805.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN48805.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN48805.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN48805.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
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DR EMBL; AE010300; AAN48805.1; -; Genomic_DNA.
DR RefSeq; NP_711787.1; NC_004342.2.
DR RefSeq; WP_000600889.1; NC_004342.2.
DR AlphaFoldDB; Q8F5R1; -.
DR STRING; 189518.LA_1606; -.
DR PaxDb; 189518-LA_1606; -.
DR EnsemblBacteria; AAN48805; AAN48805; LA_1606.
DR GeneID; 61142061; -.
DR KEGG; lil:LA_1606; -.
DR PATRIC; fig|189518.3.peg.1603; -.
DR HOGENOM; CLU_007383_1_7_12; -.
DR InParanoid; Q8F5R1; -.
DR OrthoDB; 9771073at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR CDD; cd05257; Arna_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045869; Arna-like_SDR_e.
DR InterPro; IPR026390; LegB-like.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR04180; EDH_00030; 1.
DR PANTHER; PTHR43000:SF2; BLR5989 PROTEIN; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT DOMAIN 3..303
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
SQ SEQUENCE 330 AA; 36561 MW; 88B495C834E497C8 CRC64;
MILITGADGF IGSHLTETLV RQGHEVRAFV LYNSFNSWGW LDQCPDDIKG KFEVFSGDIR
DPNGVRAAMK GCDAVLHLAA LIAIPYSYHS PDTYIDTNVK GTLNVVQAAR DLNVSKVIHT
STSEVYGTAR FVPITEEHPL QGQSPYSASK IGADQIAMSF YNSFGTPVSI IRPFNTYGPR
QSARAVIPTI ITQIAKGNRK IKLGAVHPTR DFNFVKDTVA GFIAALNSDV CVGEVINLGS
NYEISVGDTV RLIAEVMKVN VEIESDDQRL RPEKSEVERL WASNQKAKDL INWSPEYGGR
DGFKRGLSET IDWFSDIDNL SFYKTDIYNI
//
