ID Q8FM09_COREF Unreviewed; 774 AA.
AC Q8FM09; C8NJJ3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Putative membrane protein {ECO:0000313|EMBL:BAC19508.1};
OS Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS / NBRC 100395).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=196164 {ECO:0000313|EMBL:BAC19508.1, ECO:0000313|Proteomes:UP000001409};
RN [1] {ECO:0000313|EMBL:BAC19508.1, ECO:0000313|Proteomes:UP000001409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395
RC {ECO:0000313|Proteomes:UP000001409};
RX PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BA000035; BAC19508.1; -; Genomic_DNA.
DR RefSeq; WP_006768935.1; NZ_GG700685.1.
DR AlphaFoldDB; Q8FM09; -.
DR STRING; 196164.gene:10743146; -.
DR KEGG; cef:CE2698; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_1_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000001409; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001409};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..362
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 485..691
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 706..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 82674 MW; 86CBC0FE17E6FBE8 CRC64;
MFSRWGHFAY NHRRIIPLII VAAILALYFG FGTKLGERMS QEGWDDPGSS STAAAQIEME
TFGRDNNGDV VLLFTAPEGT SFDDPEVFSA VSDHLTGLRE DNPGEVSHIN SYFDTRNPSL
LSEDGTQAFA ALGLEGDGEQ TLRDFRAIED QLVPESLPGG VTTQVAGATA VADALDDGMA
GDILRAEVYA LPAVAILLLF VFGSVVAAGM PLIVGVLSIL GSLGVLSILA NITQVNVFAQ
SVVTLLGLGL AIDYGLFMVS RFREEMDKGS PIPQAVATTT ATAGKTVVFS AAMVAVALSG
LFVFPQAFLK SVAFGAISAV GLAALMSVVV LPSIFGMLGT NIDRWSLRRT SRTARRLEDT
IWFKVPSWAM KNAKLVTAAI VLVLIGLTVP LVGVKFGGIN ETYLPPTNDT RQAQEDFDDS
FAAFRTEPVK LVVTNADNNQ LIDIYVQANE VEGLTDRFSA GATTDGTTVL SAGIIDRSMN
ESVIDQLRAI DVPEGVEVYI GGTPAMEIES IEALFEKLPW MALYIVVATF ILMALVFGSL
ILPAKAIIMT VLGMGATLGI LTLMFVDGVG ADLFNFSPGP LMSPVLVLIM AIIYGLSTDY
EVFLVSRMVE ARDKGASTDD AIRYGTAHTG SIITAAALIM IVVCGAFGFS EIVMMKYIAF
GMIAALILDA TIIRMLLVPA VMHLLREDNW WAPGFIKKAY AVMGHGSDGP ETTGPTGPTR
PLDEGEEVTI HEAVPAEETV ASRSGRSTAE DEELVPFAEL MSRLENKRRS GDSD
//
