ID Q8FS05_COREF Unreviewed; 522 AA.
AC Q8FS05;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Putative aldehyde dehydrogenase {ECO:0000313|EMBL:BAC17413.1};
OS Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS / NBRC 100395).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=196164 {ECO:0000313|EMBL:BAC17413.1, ECO:0000313|Proteomes:UP000001409};
RN [1] {ECO:0000313|EMBL:BAC17413.1, ECO:0000313|Proteomes:UP000001409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395
RC {ECO:0000313|Proteomes:UP000001409};
RX PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; BA000035; BAC17413.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8FS05; -.
DR STRING; 196164.gene:10741005; -.
DR KEGG; cef:CE0603; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_0_11; -.
DR Proteomes; UP000001409; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07101; ALDH_SSADH2_GabD2; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000001409}.
FT DOMAIN 29..487
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 522 AA; 56758 MW; B81C8E699B0E5F8C CRC64;
MERMYPPRLT PGPLPRELEE HLRGLITSEA TPTIPVEAPF DATTIGHVPE GGQSCVDKAF
SLAREAQRGW EDTPHATRRS IVRTFHSLVL KHRELLMDMV QLETGKNRAA AFDEVMDVAS
TARYYAARAE KLLTPRRRQG TIPVLSSTVE HRYPLGVIGQ ISPWNYPLTL AISDAIPALL
AGNAVVSKPD ERTPFTALLV TSLLYDAGLP RDIFHTVTGP GPVVGGAIAE HCDYLMFTGS
TNTGRILGET AGRRLIGFSA ELGGKNPLII AEDADLDKAV DGAVHGTISN SGQLCVSIER
IFVVGSMYPR FVDAYVQRLQ SIRMEAGFDW DVEMGSLASQ QQLDTVTRMV DEAVSKGAEV
LTGGRARPDL GPYFYEPTVL TGVTKKMELY RHEVFGPVVY VEAVADLAEA IVYANDTDYG
LNAGIFAARD TALAAAPLIR VGGVNINDSY SATWGNIDTP LGGAKDSGLS ARHGEEGLLK
YTQTQNISEQ RYLQLRGPRS LKRKTYASLM TAGLKALAVM RR
//
