ID XYLG_BRUSU Reviewed; 511 AA.
AC Q8FUR8; G0KEE8;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722};
GN OrderedLocusNames=BRA1151, BS1330_II1142;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01722}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR EMBL; AE014292; AAN34310.1; -; Genomic_DNA.
DR EMBL; CP002998; AEM20586.1; -; Genomic_DNA.
DR RefSeq; WP_006191509.1; NZ_KN046805.1.
DR AlphaFoldDB; Q8FUR8; -.
DR SMR; Q8FUR8; -.
DR GeneID; 45054134; -.
DR KEGG; bms:BRA1151; -.
DR KEGG; bsi:BS1330_II1142; -.
DR PATRIC; fig|204722.21.peg.239; -.
DR HOGENOM; CLU_000604_92_3_5; -.
DR PhylomeDB; Q8FUR8; -.
DR Proteomes; UP000007104; Chromosome II.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03216; ABC_Carb_Monos_I; 1.
DR CDD; cd03215; ABC_Carb_Monos_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013455; ABC_transptr_XylG.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; NF040905; GguA; 1.
DR NCBIfam; TIGR02633; xylG; 1.
DR PANTHER; PTHR43790; CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED; 1.
DR PANTHER; PTHR43790:SF1; XYLOSE IMPORT ATP-BINDING PROTEIN XYLG; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51280; XYLG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT CHAIN 1..511
FT /note="Xylose import ATP-binding protein XylG"
FT /id="PRO_0000271496"
FT DOMAIN 6..244
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT DOMAIN 261..506
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ SEQUENCE 511 AA; 55851 MW; 262044FA7B92B81E CRC64;
MSEYLLEMRN IGKEFNGVKA LDGIYLKVRA GECVELCGEN GAGKSTLMKV PSGVYPHGTW
TGEIFWEGKE LKASGIRDTE AAGIVIIHQE LMMVPHLSVA ENIFLGCEPT TGGFIDYDQM
NARAAELLAR LKINDINVAL PVYHYSGGKQ QLIEIAKAIN KNAKLLILDE PTSALTASET
RVLIDLIKDF KKQGMACVYI SHKLDEVAEI SDTVTVIRDG AHIATRPMSE LTTPDIITMM
VGREMKNLFP REPHDIGEVM FEARNISCWD VTNPGRKVVD DVSFALRRGE ILGIAGLVGA
GRTELVSSLF GVWPGACQGQ VFLEGKEIKI RTPRDAVRQG ICMVPEDHKR DGILPIMPVG
HNMTISVLDR FSLRGLIDKD AELVAIQREI LRLKVKTADP MLAIASLSGG NQQKAVLSKM
MLPDPKVLIL DEPTRGVDVG AKYEIYKLIF ALARQGVSIL MVSSEMPEVL GISDRVLVIG
EGKLRGDFPN ENLTQEKVLA AAIGKPATNA A
//
