ID Q8G7K6_BIFLO Unreviewed; 351 AA.
AC Q8G7K6;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=LacI-type transcriptional regulator {ECO:0000313|EMBL:AAN24100.1};
GN OrderedLocusNames=BL0258 {ECO:0000313|EMBL:AAN24100.1};
OS Bifidobacterium longum (strain NCC 2705).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=206672 {ECO:0000313|EMBL:AAN24100.1, ECO:0000313|Proteomes:UP000000439};
RN [1] {ECO:0000313|EMBL:AAN24100.1, ECO:0000313|Proteomes:UP000000439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCC 2705 {ECO:0000313|Proteomes:UP000000439};
RX PubMed=12381787; DOI=10.1073/pnas.212527599;
RA Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G.,
RA Zwahlen M.C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.;
RT "The genome sequence of Bifidobacterium longum reflects its adaptation to
RT the human gastrointestinal tract.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
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DR EMBL; AE014295; AAN24100.1; -; Genomic_DNA.
DR RefSeq; NP_695464.1; NC_004307.2.
DR RefSeq; WP_011068391.1; NC_004307.2.
DR AlphaFoldDB; Q8G7K6; -.
DR STRING; 206672.BL0258; -.
DR EnsemblBacteria; AAN24100; AAN24100; BL0258.
DR KEGG; blo:BL0258; -.
DR PATRIC; fig|206672.9.peg.993; -.
DR HOGENOM; CLU_037628_6_0_11; -.
DR OrthoDB; 2854648at2; -.
DR PhylomeDB; Q8G7K6; -.
DR Proteomes; UP000000439; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000439};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 351 AA; 38020 MW; 4F1D9D3F2CDA08A9 CRC64;
MSGEKTAKRR VTLRDVAQAA GVSLKTASNV INGSGRMTDE TRAKVESVIK DLDYRVNVAA
RNLNRDHTGF ITLAVPSLIP PYLAELANRT IDAARQRDYS VYVTTYAEGS AKGARDLLKK
FNSTVSDGMI LSMSEVENIS PDDLKVDFPL VIVGARTTWG IVDHVTPDDV SAAAMAAGYL
YDRGSTRLAV IGARDVYDED ALLNAVEGNA QLRLRGIIEE TRRRGLSLDP QLIGNTDQDW
TIGAGARVTQ RLIDSGVPFD GVIALNDQLA IGALTALRTA GYEVPVQVQV IGFDNNEEAP
YLQIPLTTMD SRLDWTAPTA VNRILGRIDG SITKSELLTT ESQVIARAST R
//
