ID Q8I1Z8_PLAF7 Unreviewed; 560 AA.
AC Q8I1Z8;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Pre-mRNA splicing factor, putative {ECO:0000313|EMBL:CAD49123.1};
GN ORFNames=PF3D7_0403200 {ECO:0000313|EMBL:CAD49123.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD49123.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000313|EMBL:CAD49123.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C., Harris B., Harris D.,
RA Mungall K., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corto C., Cronin A., Davies R.,
RA Davies P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James D.,
RA Johnson D., Kerhornou A., Knight A., Kontfortov B., Keyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., McLean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M-A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AL844503; CAD49123.1; -; Genomic_DNA.
DR RefSeq; XP_001351343.1; XM_001351307.1.
DR AlphaFoldDB; Q8I1Z8; -.
DR SMR; Q8I1Z8; -.
DR IntAct; Q8I1Z8; 8.
DR STRING; 36329.Q8I1Z8; -.
DR PaxDb; 5833-PFD0150w; -.
DR EnsemblProtists; CAD49123; CAD49123; PF3D7_0403200.
DR GeneID; 812590; -.
DR KEGG; pfa:PF3D7_0403200; -.
DR VEuPathDB; PlasmoDB:PF3D7_0403200; -.
DR HOGENOM; CLU_487056_0_0_1; -.
DR InParanoid; Q8I1Z8; -.
DR OMA; NEHVSYE; -.
DR OrthoDB; 249277at2759; -.
DR Proteomes; UP000001450; Chromosome 4.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR022209; CWC25.
DR Pfam; PF12542; CWC25; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT REGION 74..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..197
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 69423 MW; 124D6F2B97520DF5 CRC64;
MENIYNDMEE YGKICQLYQE KKQKKEKKKN KDDDNEENIL DEDILWMYET KEEKEIKEQE
EYLLGKKIDM QKLMQDDEEE KDQGGILNKN NNNKNNNNNN KNNIDNLNKI REDPLTLIKK
IELKKKKMMD EQKRLLDLQE SRENQQNKYD INKTNSRPIK KVKDCEEELR RKINKLKEMN
RERERKKKKR NKDRKKKERS EKKYSNSEMH DTSNESYTNS DTYDNTVTST NIETNMESER
KKYQHERFSD IEREIKRRRK DEKERDRERE RERERERERR RYVEREKRRI MERERRRAME
RQEEMERERE REWERERERK RRKELERERR KEMERRKELE RERRKYLDKE RTKRYIRSNS
SSIYNDRERK KYEDRKRKKK NHIRSISQST YSYDKRERKK YTNRDRDKRR DTKSSSISYI
EKEKKKKNNK KKDRKKNVSS DSSQSDNKTV KDKKEKKKKE REQFKQKENH DNLNSASNEH
VSYESDTYEN NKNDKEINSQ SDKKLNSQSD KKLNSQSDKK LNSQSDKEIN SQNDKEVNSQ
SDKEINSQSD KGINSQSDND
//
