ID Q8I492_PLAF7 Unreviewed; 1434 AA.
AC Q8I492;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 10-FEB-2021, entry version 106.
DE SubName: Full=Mature parasite-infected erythrocyte surface antigen {ECO:0000313|EMBL:CAD51374.1};
GN ORFNames=PF3D7_0500800 {ECO:0000313|EMBL:CAD51374.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51374.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000313|EMBL:CAD51374.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL844504; CAD51374.1; -; Genomic_DNA.
DR RefSeq; XP_001351567.1; XM_001351531.1.
DR IntAct; Q8I492; 27.
DR DrugBank; DB11638; Artenimol.
DR SwissPalm; Q8I492; -.
DR PRIDE; Q8I492; -.
DR EnsemblProtists; CAD51374; CAD51374; PF3D7_0500800.
DR GeneDB; PF3D7_0500800.1:pep; -.
DR GeneID; 812891; -.
DR KEGG; pfa:PF3D7_0500800; -.
DR VEuPathDB; PlasmoDB:PF3D7_0500800; -.
DR HOGENOM; CLU_252288_0_0_1; -.
DR InParanoid; Q8I492; -.
DR OMA; EIMNEDV; -.
DR Proteomes; UP000001450; Chromosome 5.
DR GO; GO:0020002; C:host cell plasma membrane; IDA:GeneDB.
DR CDD; cd06257; DnaJ; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR009484; DUF1103.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF06513; DUF1103; 3.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT DOMAIN 1337..1403
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 200..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1012..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1146..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 139..166
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 200..342
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..421
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..552
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..865
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..880
FT /note="Basic"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..991
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1098
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1199
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1200..1271
FT /note="Acidic"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1434 AA; 168288 MW; AB0005F9DC26C989 CRC64;
MEVICRNLCY DKKNNMMENE GNKVKKVYNN SSLKKYMKFC LCTIICVFLL DIYTNCESPT
YSYSSIKNNN DRYVRILSET EPPMSLEEIM RTFDEDHLYS IRNYIECLRN APYIDDPLWG
SVVTDKRNNC LQHIKLLEMQ ESERRKQQEE ENAKDIEEIR KKEKEYLMKE LEEMDESDVE
KAFRELQFIK LRDRTRPRKH VNVMGESKET DESKETDESK ETGESKETGE SKETGESKET
GESKETGESK ETGESKETGE SKETGESKET GESKETGESK ETGESKETGE SKETGESKET
GESKETRIYE ETKYNKITSE FRETENVKIT EESKDREGNK VSGPYENSEN SNVTSESEET
KKLAEKEENE GEKLGENVND GASENSEDPK KLTEQEENGT KESSEETKDD KPEENEKKAD
NKKKSKKKKK SFFQMLGCNF LCNKNIETDD EEETLVVKDD AKKKHKFLRE ANTEKNDNEK
KDKLLGEGDK EDVKEKNDEQ KDKVLGEGDK EDVKEKNDEQ KDKVLGEGDK EDVKEKNDGK
KDKVIGSEKT QKEIKEKVEK RVKKKCKKKV KKGIKENDTE GNDKVKGPEI IIEEVKEEIK
KQVEDGIKEN DTEGNDKVKG PEIITEEVKE EIKKQVEEGI KENDTEGNDK VKGPEIITEE
VKEEIKKQVE EGIKENDTES KDKLIGQEII TEEVKEGIKE NDTENKDKVI GQEIITEEVK
EGIKENDTEN KDKVIGQEII TEEVKKEIEK QEEKGNKENI LEIKDIVIGQ EVIIEEVKKV
IKKKVEKGIK ENHTESKDKV IGQEIIVEEV KEEIEKQVEE GIKENDTESK DKVIGQEVIK
GDVNEEGPEN KDKVTKQEKV KEVKKEVKKK VKKRVKKRNN KNERKDNVIG KEIMKEDVNE
KDTANKDKEI EQEKEKEEVK EKEEVKEKEE VKEKEEVKEK EEVKEKEEVK EKEEVKEKEE
VKEKDTESKD KEIEQEKEKE EVKEVKEKDT ENKDKVIGQE IIIEEIKKEV KKRVKKRNNK
NENKDNVIVQ EIMNEDVNEK DTANKDKVIE QEKEKEEVKE KEEVKEKEEV KEKEEVKEKE
EVKEKEEVKE KDTESKDNVI VQEIMNEDVN EKDTESKDKM IGKEVIIEEV KEEVKKRVNK
EVNKRVNRRN RKNERKDVIE QEIVSEEVNE KDTKNNDKKI GKRVKKPIDD CKKEREVQEE
SEEESEEESE EESEEESEEE SEEESEEESE EESEEESEEE SEEESEEESE EESEEESEEE
SEEESEEESD EEKNTSGLVH RRNCKKEKKY NNGELEEYYK EKQNEEYFDE EYIIQSKEHN
TLNTFPNMAL NEDFRREFHN ILSIHEDTDL MELKRILYNL FLEYNPHMNN KQKAELDKKF
SEMNVVHQIL NYEERIRMYE ENAARGRLNT VILDPIITFN VIFGDDTMFK FIDE
//
