ID Q8I4I0_CAEEL Unreviewed; 287 AA.
AC Q8I4I0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0000313|EMBL:CAD56588.1};
GN Name=spe-54 {ECO:0000313|EMBL:CAD56588.1};
GN ORFNames=CELE_F55H12.5 {ECO:0000313|EMBL:CAD56588.1}, F55H12.5
GN {ECO:0000313|WormBase:F55H12.5};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAD56588.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAD56588.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAD56588.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284601; CAD56588.1; -; Genomic_DNA.
DR RefSeq; NP_492395.2; NM_059994.5.
DR AlphaFoldDB; Q8I4I0; -.
DR SMR; Q8I4I0; -.
DR STRING; 6239.F55H12.5.1; -.
DR PaxDb; 6239-F55H12-5; -.
DR PeptideAtlas; Q8I4I0; -.
DR EnsemblMetazoa; F55H12.5.1; F55H12.5.1; WBGene00010136.
DR EnsemblMetazoa; F55H12.5.2; F55H12.5.2; WBGene00010136.
DR EnsemblMetazoa; F55H12.5.3; F55H12.5.3; WBGene00010136.
DR GeneID; 172700; -.
DR KEGG; cel:CELE_F55H12.5; -.
DR UCSC; F55H12.5; c. elegans.
DR AGR; WB:WBGene00010136; -.
DR WormBase; F55H12.5; CE32441; WBGene00010136; -.
DR eggNOG; KOG4228; Eukaryota.
DR HOGENOM; CLU_875231_0_0_1; -.
DR InParanoid; Q8I4I0; -.
DR OMA; PLVIVCK; -.
DR OrthoDB; 2880984at2759; -.
DR PhylomeDB; Q8I4I0; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00010136; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR PANTHER; PTHR46163:SF14; TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q8I4I0,
KW ECO:0007829|PeptideAtlas:Q8I4I0};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 78..280
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
SQ SEQUENCE 287 AA; 32223 MW; 3C4DFD3FB51B536C CRC64;
MADTVQTNGR ASLLAAVNNR ASTRSTRKKK TTMLSPKKFC DFINSKTNSK SFEAGVAEFY
KETYLESPTF FNYFKSPKDK NFSENVWLYD ATRVIVPGVD YYHASWVDGL KPNQYILAQA
PRDASAAKDF FKLLEHVKAE GLIVAEGADE FSSAITAKFE KGTGKNDFVS TAVIKENGLH
LKAIKFCRWA EPLSAIEIND MLEKSRKYLG CPLKGPLVIV CKDGAAKSGL VAFIDTEADR
LMKHGKAKHT DTIKQIRFMR SNTFDTFDSY DLGINSLIEL CNRYKKK
//
