ID Q8I4R0_PLAF7 Unreviewed; 453 AA.
AC Q8I4R0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 24-JAN-2024, entry version 111.
DE SubName: Full=Esterase, putative {ECO:0000313|EMBL:CZT99679.1};
DE EC=3.1.-.- {ECO:0000313|EMBL:CZT99679.1};
GN ORFNames=PF3D7_1252600 {ECO:0000313|EMBL:CZT99679.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT99679.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CZT99679.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN999947; CZT99679.1; -; Genomic_DNA.
DR RefSeq; XP_001350908.1; XM_001350872.1.
DR AlphaFoldDB; Q8I4R0; -.
DR IntAct; Q8I4R0; 1.
DR STRING; 36329.Q8I4R0; -.
DR ESTHER; plafa-PFL2530W; Plasmodium_subtelomeric_PST-A.
DR PaxDb; 5833-PFL2530w; -.
DR EnsemblProtists; CZT99679; CZT99679; PF3D7_1252600.
DR GeneID; 811556; -.
DR KEGG; pfa:PF3D7_1252600; -.
DR VEuPathDB; PlasmoDB:PF3D7_1252600; -.
DR HOGENOM; CLU_015822_1_1_1; -.
DR InParanoid; Q8I4R0; -.
DR OMA; HFKQPTA; -.
DR OrthoDB; 238123at2759; -.
DR PhylomeDB; Q8I4R0; -.
DR Proteomes; UP000001450; Chromosome 12.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0016298; F:lipase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR022742; Hydrolase_4.
DR InterPro; IPR006494; PST_A.
DR NCBIfam; TIGR01607; PST-A; 1.
DR PANTHER; PTHR11614:SF87; MONOGLYCERIDE LIPASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF12146; Hydrolase_4; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CZT99679.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT DOMAIN 88..140
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT DOMAIN 171..347
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
SQ SEQUENCE 453 AA; 52892 MW; A245677B9EF40BA6 CRC64;
MVENELINEN NLTHKRLDGT PKLDSFFNKD GLLIRTYSWT VKKAIGIIVL IHGLNSHFRL
QYLKHNADII SNDKAVLINS DEYYIYKDSW IERLNNEGYS VYGLDLQSHG KSDGWQNLRG
NVNYFDDLVY DVIQYINKIN SSVIKEREDP KEYSYSDYNY NFKNKMPNIV RSPLYIMGLS
MGGNIALRVL ELIGKSKEVN DNLNVKGCIS LAGMISIDEN ASKIPFKFKY FFIPLSRYVA
YFFPTFRPSP NLNFEKFPYI NDIINFDKNR YDKWITMRFA HQLIEATRNL RDDMKYIPKD
IPVLFIHSKD DCACYYEGVE IFFNKLGINN KELHTIYDMD HLLTMEPGNE RVLDKVITWI
KGLGEENDDN NSAQCMDDTN MLNAISHIED EIIKRSNERV KLEKQNNDDF IAQKGNIEMF
TVPLDNEKDL CNISDKEIIE NNMTHSEVEL VIN
//
