ID Q8I4W4_PLAF7 Unreviewed; 261 AA.
AC Q8I4W4;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE RecName: Full=Signal recognition particle receptor subunit beta {ECO:0000256|ARBA:ARBA00020256};
GN ORFNames=PF3D7_1246800 {ECO:0000313|EMBL:CZT99622.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT99622.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CZT99622.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the SRP receptor beta subunit family.
CC {ECO:0000256|ARBA:ARBA00005619}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; LN999947; CZT99622.1; -; Genomic_DNA.
DR RefSeq; XP_001350853.1; XM_001350817.1.
DR AlphaFoldDB; Q8I4W4; -.
DR SMR; Q8I4W4; -.
DR STRING; 36329.Q8I4W4; -.
DR DrugBank; DB11638; Artenimol.
DR SwissPalm; Q8I4W4; -.
DR PaxDb; 5833-PFL2245w; -.
DR EnsemblProtists; CZT99622; CZT99622; PF3D7_1246800.
DR GeneID; 811501; -.
DR KEGG; pfa:PF3D7_1246800; -.
DR VEuPathDB; PlasmoDB:PF3D7_1246800; -.
DR HOGENOM; CLU_046625_2_0_1; -.
DR InParanoid; Q8I4W4; -.
DR OMA; INLNEFH; -.
DR OrthoDB; 276497at2759; -.
DR PhylomeDB; Q8I4W4; -.
DR Proteomes; UP000001450; Chromosome 12.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR CDD; cd04105; SR_beta; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR019009; SRP_receptor_beta_su.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF41; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1; 1.
DR Pfam; PF09439; SRPRB; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|EMBL:CZT99622.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 261 AA; 30624 MW; 93D928DDA578A276 CRC64;
MDILNKIIKD IIYKIKIYHV KYGIHLNDFH NLLFVITLLF GLVFLLYLLL ILFNIFFKKS
KANNVVLLLG PCDSGKTTFL FKLKTDKLCR TVPSMKENIA FIFLKNKKKQ KCIRFVDFPG
HPKLSYSLNK YFNITNVIVY MIDSSDRQSL KFVAEKLFEL FTNKVIVKKK IPFIIVCNKT
DLCNSRPKQV IKEDLEREIE ILKMSKYNNL DDDCIDETEC FLGANSEFFR FEKAPCHIEL
CSASVKNNNV DEIIEFVEKH Y
//
