ID Q8IAU0_PLAF7 Unreviewed; 303 AA.
AC Q8IAU0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Protein phosphatase PPM7, putative {ECO:0000313|EMBL:CAD51270.1};
DE EC=3.1.3.16 {ECO:0000313|EMBL:CAD51270.1};
GN ORFNames=PF3D7_0810500 {ECO:0000313|EMBL:CAD51270.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD51270.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C., Harris B., Harris D.,
RA Mungall K., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corto C., Cronin A., Davies R.,
RA Davies P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James D.,
RA Johnson D., Kerhornou A., Knight A., Kontfortov B., Keyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., McLean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M-A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR EMBL; AL844507; CAD51270.1; -; Genomic_DNA.
DR RefSeq; XP_001349421.1; XM_001349385.1.
DR AlphaFoldDB; Q8IAU0; -.
DR SMR; Q8IAU0; -.
DR IntAct; Q8IAU0; 1.
DR STRING; 36329.Q8IAU0; -.
DR PaxDb; 5833-MAL8P1-108; -.
DR EnsemblProtists; CAD51270; CAD51270; PF3D7_0810500.
DR GeneID; 2655394; -.
DR KEGG; pfa:PF3D7_0810500; -.
DR VEuPathDB; PlasmoDB:PF3D7_0810500; -.
DR HOGENOM; CLU_013173_1_6_1; -.
DR InParanoid; Q8IAU0; -.
DR OMA; TYEDEFF; -.
DR OrthoDB; 11028at2759; -.
DR PhylomeDB; Q8IAU0; -.
DR Proteomes; UP000001450; Chromosome 8.
DR GO; GO:0008287; C:protein serine/threonine phosphatase complex; ISS:GeneDB.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; ISS:GeneDB.
DR GO; GO:0006470; P:protein dephosphorylation; ISS:GeneDB.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832:SF876; PROTEIN PHOSPHATASE 1G; 1.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CAD51270.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT DOMAIN 14..300
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 303 AA; 34520 MW; 01D5D0C519E19435 CRC64;
MPVINGAHVI SMKNYTLVSD AYGEKGVKKV YEDEYLICEN LKSFNKNLHP NFNFACFCLF
DGHNGKNTAM FLKRNLAQEL SNSFLEMQNT YDSSLPIPDH FIKISVNNTC KRIDERIAQE
YPNSRDGATC VIVLIKDEYA YIINIGDSCA YLCRYLNNSN QAIELVDIHK PWVITEKERI
IKHGGTIENG RVNDIIDVTR SFGDLSLKKY GLLCTGTFKK FKINSDDNFI ILGTDGFFGS
VDINYVINEI TNLSKKEERL VNVEKKKTVF DAKSICNIMV EHAIVDKKSQ DNVTVVLIKF
LHK
//
