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Database: UniProt
Entry: Q8IBT4_PLAF7
LinkDB: Q8IBT4_PLAF7
Original site: Q8IBT4_PLAF7 
ID   Q8IBT4_PLAF7            Unreviewed;       546 AA.
AC   Q8IBT4;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   28-FEB-2018, entry version 89.
DE   SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:CAD50914.1};
DE            EC=2.8.1.7 {ECO:0000313|EMBL:CAD50914.1};
GN   ORFNames=PF3D7_0716600 {ECO:0000313|EMBL:CAD50914.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAD50914.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844506; CAD50914.1; -; Genomic_DNA.
DR   RefSeq; XP_001349069.1; XM_001349033.1.
DR   ProteinModelPortal; Q8IBT4; -.
DR   EnsemblProtists; CAD50914; CAD50914; PF3D7_0716600.
DR   GeneDB; PF3D7_0716600.1:pep; -.
DR   GeneID; 2655112; -.
DR   KEGG; pfa:PF07_0068; -.
DR   EuPathDB; PlasmoDB:PF3D7_0716600; -.
DR   HOGENOM; HOG000017511; -.
DR   InParanoid; Q8IBT4; -.
DR   OMA; ANTWGEA; -.
DR   PhylomeDB; Q8IBT4; -.
DR   Proteomes; UP000001450; Chromosome 7.
DR   GO; GO:0020011; C:apicoplast; IDA:GeneDB.
DR   GO; GO:0031071; F:cysteine desulfurase activity; IGI:GeneDB.
DR   GO; GO:0006534; P:cysteine metabolic process; IDA:GeneDB.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 3.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF00266; Aminotran_5; 2.
DR   SUPFAM; SSF53383; SSF53383; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transferase {ECO:0000313|EMBL:CAD50914.1}.
FT   DOMAIN       81    388       Aminotran_5. {ECO:0000259|Pfam:PF00266}.
FT   DOMAIN      462    528       Aminotran_5. {ECO:0000259|Pfam:PF00266}.
SQ   SEQUENCE   546 AA;  64561 MW;  DD3DFAF06AD9D66A CRC64;
     MLRGPRCLYI YLFFVFLPFS FCYIRNNDNR FVYIVKSIRK GPNIKLRLTK DEKPNIDNHI
     IDYFKNVREH FPFFKENKSL IYFDSAATTH KPSCVIEKMS EFYKKENSNI HRGIYKLSHN
     ATNNYEKVRE TIKEYINCEK NDNIIFTNGS TYGLNVVCKM MIEEIIKKEE DEIYLSYMEH
     HSNIIPWQEY INKEKKGRIK YVPLNKSGYI NIKKLISNMN INTKVISICH ASNVIGNIQN
     IEKIIKKIKN VYPHIIIIID ASQSFAHIKY DIKKMKKNKS CPDILITSGH KFCASLGTGF
     IFINKELSSK YKFKPLLYGS NIITNVSKYK SKFVTSLSEL LETGTQNIPG ILSMGISLEF
     FKKINWNYVY QYEMYLYDLF IYYMNKYMKN HFVQLPNLNL SYKKENINYK SHMQTHPPVH
     KYNDEQNFTN DHNITQSKQT KSIHSQHDTF KIYTHDTRKY GLKKIGILPL WSNTFSSFDL
     VTFLDFKNIC IRAGHHCASL LHKYYLKVPD TSRISIYFYN TPQEIKYLAQ QIASTSFMLN
     EMKNEK
//
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