ID Q8KBU3_CHLTE Unreviewed; 950 AA.
AC Q8KBU3;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 134.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA1 {ECO:0000313|EMBL:AAM72914.1};
GN OrderedLocusNames=CT1689 {ECO:0000313|EMBL:AAM72914.1};
OS Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
OS (Chlorobium tepidum).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Chlorobaculum.
OX NCBI_TaxID=194439 {ECO:0000313|EMBL:AAM72914.1, ECO:0000313|Proteomes:UP000001007};
RN [1] {ECO:0000313|EMBL:AAM72914.1, ECO:0000313|Proteomes:UP000001007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49652 / DSM 12025 / NBRC 103806 / TLS
RC {ECO:0000313|Proteomes:UP000001007};
RX PubMed=12093901; DOI=10.1073/pnas.132181499;
RA Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J.,
RA Deboy R., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D.,
RA Durkin A.S., Kolonay J.L., Yang F., Holt I., Umayam L.A., Mason T.,
RA Brenner M., Shea T.P., Parksey D., Nierman W.C., Feldblyum T.V.,
RA Hansen C.L., Craven M.B., Radune D., Vamathevan J., Khouri H., White O.,
RA Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A.,
RA Fraser C.M.;
RT "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic,
RT anaerobic, green-sulfur bacterium.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; AE006470; AAM72914.1; -; Genomic_DNA.
DR RefSeq; NP_662572.1; NC_002932.3.
DR RefSeq; WP_010933353.1; NC_002932.3.
DR AlphaFoldDB; Q8KBU3; -.
DR STRING; 194439.CT1689; -.
DR EnsemblBacteria; AAM72914; AAM72914; CT1689.
DR KEGG; cte:CT1689; -.
DR PATRIC; fig|194439.7.peg.1525; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_2_1_10; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000001007; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001007};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 609..939
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 950 AA; 104912 MW; B6DCFCB7F6AF3918 CRC64;
MDFSHISIRG ARVHNLRNIS LDIPRNKLVV ITGISGSGKS SLAFDTIYAE GQRRFMETLS
PYARQFIGNI ERPDVDFIEG LSPVISIDQK STNRSPRSTV GTVTEIHDFV RLLYAKAGRR
YDPVTGQMLQ KQSEESIREA IMVLPEGTKL QILSPLVTGR KGHYRELFDR LIKKGYLRAR
IDGEYVEMSA GMQLERYKSH NIELVIDRLV AGPGIGERLT QAVKLAISMS EHKSSVICDT
DDPERGELYF STQYAYADGT VPVDVLAPNQ FSFNSPYGAC PECNGLGEVM QLSAELMVPD
MTRSLEEGAI EPFGKPGKRN LWQVIRAIAK KYGFSLTTPV AEIPVEAFNI LLYGSGSKTF
DVGYSYAGKE HLYPQTFQGA VPYVEEVRMN ASTSKLREWA ESFMIRQTCP VCGGARLKQE
SLHVKVDGLN IAEVEALPLP EALEFFRALP PKLTTKEKLV AAPVLHEITK RLDFLLNVGL
GYLTLDRNSQ TLSGGEAQRI RLASQLGSQL SGVLYVLDEP SIGLHQRDNH KLIDSLRRLR
DLGNTVLVVE HDKDTMLQAD QIIDLGPGAG EHGGLVVAQG TASTLGPESV TAGYLNGTLS
VSFPPSKKKK SEQRYLKLKG CRGNNLKQVD AEFPLGSLIS VTGVSGSGKS SLINETLYPL
LARHFYRSKI LALPCDGVEG IELIDKVVNV DQSPIGRTPR SNPATYTGAF TFIRDFFTRL
PEAQIRGYKA GRFSFNVKGG RCEVCQGAGT RKIEMNFLPD VYVQCEHCKG KRYNRETLQV
KYKGKSIADV LEMPIEEAAL FFEDFPRIRR ILDTMQSVGL GYLKLGQPSP LLSGGEAQRI
KLSAELAKIQ TGKTLYILDE PTTGLHFQDI QHLLAVLRKL VEKGNTVIVI EHNLDIVRNS
DWIIDLGPEG GNGGGHIVAT GTPEEIARRS DTHTGHYLKL DAGDLLTDTD
//
