ID Q8KCH4_CHLTE Unreviewed; 505 AA.
AC Q8KCH4;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Serine protease {ECO:0000313|EMBL:AAM72675.1};
GN OrderedLocusNames=CT1447 {ECO:0000313|EMBL:AAM72675.1};
OS Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
OS (Chlorobium tepidum).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Chlorobaculum.
OX NCBI_TaxID=194439 {ECO:0000313|EMBL:AAM72675.1, ECO:0000313|Proteomes:UP000001007};
RN [1] {ECO:0000313|EMBL:AAM72675.1, ECO:0000313|Proteomes:UP000001007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49652 / DSM 12025 / NBRC 103806 / TLS
RC {ECO:0000313|Proteomes:UP000001007};
RX PubMed=12093901; DOI=10.1073/pnas.132181499;
RA Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J.,
RA Deboy R., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D.,
RA Durkin A.S., Kolonay J.L., Yang F., Holt I., Umayam L.A., Mason T.,
RA Brenner M., Shea T.P., Parksey D., Nierman W.C., Feldblyum T.V.,
RA Hansen C.L., Craven M.B., Radune D., Vamathevan J., Khouri H., White O.,
RA Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A.,
RA Fraser C.M.;
RT "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic,
RT anaerobic, green-sulfur bacterium.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
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DR EMBL; AE006470; AAM72675.1; -; Genomic_DNA.
DR RefSeq; NP_662333.1; NC_002932.3.
DR RefSeq; WP_010933114.1; NC_002932.3.
DR AlphaFoldDB; Q8KCH4; -.
DR STRING; 194439.CT1447; -.
DR MEROPS; S01.453; -.
DR EnsemblBacteria; AAM72675; AAM72675; CT1447.
DR KEGG; cte:CT1447; -.
DR PATRIC; fig|194439.7.peg.1313; -.
DR eggNOG; COG0265; Bacteria.
DR HOGENOM; CLU_020120_1_1_10; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000001007; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 2.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:AAM72675.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001007};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..505
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004309160"
FT DOMAIN 294..385
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 401..496
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 144
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 174
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 250
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 505 AA; 53528 MW; C7D762FA2320BDCE CRC64;
MKKKLTMLKS AALVSVGITA GALAFSNLDF SFNGGGNNGF MVSSHPNSSI AAETLRNHPI
RTLNDLNDAF VDIAESATPS VVTIYTETEV DRRIMTPFDF FGKSFGEMFD FPLPEEPNVR
KEVIHGLGSG VIVSQDGYIL TNNHVIDQAG SIAVMTSDNR KFKAKIVGTD PRTDLAVLKI
SGSGLKPIAF GDSDKLRVGE WVLAIGSPLG ENLARTVTQG IVSAKGRVNV GVADYENFIQ
TDAAINPGNS GGPLVNIGGE LVGINTAIAS RTGGFEGIGF AVPSNMAYRV YTSLVKNGKV
ERGYLGVTIQ DIDENIAKGL QLKSPEGVLV GTVMQGGPAA RAGLKSGDVI LEFNGRKVNS
AAELRNRIAA MAPGSSAAIR INRDGAILTL NARLESLPDN ATASARSTES KNELLGFSVA
PLTPELAGRL NLKADSRRIV VTSVSKSSRA FSVGLRPGDV VISVDKKPVD SVAAFNAIVK
NKKRGDLLFL LVERGWSRMY FAFNL
//
