ID Q8MM14_DROME Unreviewed; 902 AA.
AC Q8MM14;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 179.
DE SubName: Full=Glutamate NMDA receptor subunit variant NR2-a {ECO:0000313|EMBL:AAL12478.1};
DE SubName: Full=Glutamate NMDA receptor subunit variant NR2-b {ECO:0000313|EMBL:AAL12479.1};
DE SubName: Full=NMDA receptor 2, isoform A {ECO:0000313|EMBL:AAN09051.2};
DE SubName: Full=NMDA receptor 2, isoform B {ECO:0000313|EMBL:AAF45639.3};
DE SubName: Full=NMDA receptor 2, isoform D {ECO:0000313|EMBL:ACZ95172.1};
DE SubName: Full=NMDA receptor subunit 2-1c {ECO:0000313|EMBL:AAT40457.1};
DE SubName: Full=NMDA receptor subunit 2-1d {ECO:0000313|EMBL:AAT40458.1};
DE SubName: Full=NMDA receptor subunit 2-1e {ECO:0000313|EMBL:AAT40459.1};
DE SubName: Full=NMDA receptor subunit 2-1f {ECO:0000313|EMBL:AAT40460.1};
GN Name=Nmdar2 {ECO:0000313|EMBL:AAF45639.3,
GN ECO:0000313|FlyBase:FBgn0053513};
GN Synonyms=79G8T {ECO:0000313|EMBL:AAF45639.3}, anon-sts34
GN {ECO:0000313|EMBL:AAF45639.3}, CG14793 {ECO:0000313|EMBL:AAF45639.3},
GN CG14794 {ECO:0000313|EMBL:AAF45639.3}, CT34603
GN {ECO:0000313|EMBL:AAF45639.3}, Dmel\CG33513
GN {ECO:0000313|EMBL:AAF45639.3}, DmelNmdar2
GN {ECO:0000313|EMBL:AAF45639.3}, dnmdar-II
GN {ECO:0000313|EMBL:AAF45639.3}, dNR2 {ECO:0000313|EMBL:AAF45639.3},
GN DrNR2 {ECO:0000313|EMBL:AAF45639.3}, dsNR2
GN {ECO:0000313|EMBL:AAF45639.3}, EG:80H7.7
GN {ECO:0000313|EMBL:AAF45639.3}, ESTS:79G8T
GN {ECO:0000313|EMBL:AAF45639.3}, NMDA-R2 {ECO:0000313|EMBL:AAF45639.3},
GN NMDAR {ECO:0000313|EMBL:AAF45639.3}, NMDAR2
GN {ECO:0000313|EMBL:AAF45639.3}, NR2 {ECO:0000313|EMBL:AAF45639.3}, nr2
GN {ECO:0000313|EMBL:AAF45639.3};
GN ORFNames=CG33513 {ECO:0000313|EMBL:AAF45639.3,
GN ECO:0000313|FlyBase:FBgn0053513}, Dmel_CG33513
GN {ECO:0000313|EMBL:AAF45639.3};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAL12478.1};
RN [1] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A.,
RA An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E.,
RA Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C.,
RA Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A.,
RA Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C.,
RA Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G.,
RA Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.,
RA Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000313|EMBL:AAL12478.1}
RP NUCLEOTIDE SEQUENCE.
RA Fu T.-F., Chiang A.-S.;
RT "Cloning and characterization of cDNA encoding the Drosophila NMDA receptor
RT subunit 2.";
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537568;
RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster
RT euchromatic genome sequence.";
RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN [4] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [5] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537573;
RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M.,
RA Celniker S.E.;
RT "The transposable elements of the Drosophila melanogaster euchromatin: a
RT genomics perspective.";
RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN [6] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537574;
RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA Karpen G.H.;
RT "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.";
RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN [7] {ECO:0000313|EMBL:AAT40457.1}
RP NUCLEOTIDE SEQUENCE.
RA Xia S., Miyashita T., Fu T.-F., Lin W.-Y., Wu C.-L., Grady L., Lin I.-R.,
RA Saitoe M., Tully T., Chiang A.-S.;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:AAL12478.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15823532; DOI=10.1016/j.cub.2005.02.059;
RA Xia S., Miyashita T., Fu T.-F., Lin W.-Y., Wu C.-L., Pyzocha L., Lin I.-R.,
RA Saitoe M., Tully T., Chiang A.-S.;
RT "NMDA receptors mediate olfactory learning and memory in Drosophila.";
RL Curr. Biol. 15:603-615(2005).
RN [9] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA Ashburner M., Anxolabehere D.;
RT "Combined evidence annotation of transposable elements in genome
RT sequences.";
RL PLoS Comput. Biol. 1:166-175(2005).
RN [10] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RA Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA Svirskas R., Rubin G.;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569856; DOI=10.1126/science.1139815;
RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.";
RL Science 316:1586-1591(2007).
RN [12] {ECO:0000313|EMBL:AAF45639.3, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569867; DOI=10.1126/science.1139816;
RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA Dimitri P., Karpen G.H., Celniker S.E.;
RT "Sequence finishing and mapping of Drosophila melanogaster
RT heterochromatin.";
RL Science 316:1625-1628(2007).
RN [13] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26109357; DOI=.1534/g3.115.018929;
RG FlyBase Consortium;
RA Matthews B.B., Dos Santos G., Crosby M.A., Emmert D.B., St Pierre S.E.,
RA Gramates L.S., Zhou P., Schroeder A.J., Falls K., Strelets V., Russo S.M.,
RA Gelbart W.M., null;
RT "Gene Model Annotations for Drosophila melanogaster: Impact of High-
RT Throughput Data.";
RL G3 (Bethesda) 5:1721-1736(2015).
RN [14] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26109356; DOI=.1534/g3.115.018937;
RG FlyBase Consortium;
RA Crosby M.A., Gramates L.S., Dos Santos G., Matthews B.B., St Pierre S.E.,
RA Zhou P., Schroeder A.J., Falls K., Emmert D.B., Russo S.M., Gelbart W.M.,
RA null;
RT "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.";
RL G3 (Bethesda) 5:1737-1749(2015).
RN [15] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25589440;
RA Hoskins R.A., Carlson J.W., Wan K.H., Park S., Mendez I., Galle S.E.,
RA Booth B.W., Pfeiffer B.D., George R.A., Svirskas R., Krzywinski M.,
RA Schein J., Accardo M.C., Damia E., Messina G., Mendez-Lago M.,
RA de Pablos B., Demakova O.V., Andreyeva E.N., Boldyreva L.V., Marra M.,
RA Carvalho A.B., Dimitri P., Villasante A., Zhimulev I.F., Rubin G.M.,
RA Karpen G.H., Celniker S.E.;
RT "The Release 6 reference sequence of the Drosophila melanogaster genome.";
RL Genome Res. 25:445-458(2015).
RN [16] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RG Berkeley Drosophila Genome Project;
RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C.,
RA Rubin G.;
RT "Drosophila melanogaster release 4 sequence.";
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
RN [17] {ECO:0000313|EMBL:AAF45639.3}
RP NUCLEOTIDE SEQUENCE.
RG FlyBase;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; AE014298; AAF45639.3; -; Genomic_DNA.
DR EMBL; AY050490; AAL12478.1; -; mRNA.
DR EMBL; AY050491; AAL12479.1; -; mRNA.
DR EMBL; AE014298; AAN09051.2; -; Genomic_DNA.
DR EMBL; AY616144; AAT40457.1; -; mRNA.
DR EMBL; AY616145; AAT40458.1; -; mRNA.
DR EMBL; AY616146; AAT40459.1; -; mRNA.
DR EMBL; AY616147; AAT40460.1; -; mRNA.
DR EMBL; AE014298; ACZ95172.1; -; Genomic_DNA.
DR RefSeq; NP_001014715.1; NM_001014715.2.
DR RefSeq; NP_001014716.1; NM_001014716.2.
DR RefSeq; NP_001162635.1; NM_001169164.1.
DR AlphaFoldDB; Q8MM14; -.
DR SMR; Q8MM14; -.
DR EnsemblMetazoa; FBtr0091453; FBpp0089172; FBgn0053513.
DR EnsemblMetazoa; FBtr0091454; FBpp0089173; FBgn0053513.
DR EnsemblMetazoa; FBtr0301842; FBpp0291056; FBgn0053513.
DR GeneID; 31107; -.
DR UCSC; CG33513-RA; d. melanogaster.
DR AGR; FB:FBgn0053513; -.
DR CTD; 31107; -.
DR FlyBase; FBgn0053513; Nmdar2.
DR VEuPathDB; VectorBase:FBgn0053513; -.
DR GeneTree; ENSGT00940000172347; -.
DR HOGENOM; CLU_002039_3_0_1; -.
DR OMA; DANCALM; -.
DR OrthoDB; 1034721at2759; -.
DR BioGRID-ORCS; 31107; 0 hits in 3 CRISPR screens.
DR ChiTaRS; RnrS; fly.
DR GenomeRNAi; 31107; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0053513; Expressed in brain and 3 other cell types or tissues.
DR ExpressionAtlas; Q8MM14; baseline and differential.
DR GO; GO:0008328; C:ionotropic glutamate receptor complex; IPI:FlyBase.
DR GO; GO:0016020; C:membrane; IDA:FlyBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098839; C:postsynaptic density membrane; IBA:GO_Central.
DR GO; GO:0008066; F:glutamate receptor activity; IBA:GO_Central.
DR GO; GO:0004972; F:NMDA glutamate receptor activity; ISS:FlyBase.
DR GO; GO:1904315; F:transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential; IBA:GO_Central.
DR GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:FlyBase.
DR GO; GO:0007616; P:long-term memory; IMP:FlyBase.
DR GO; GO:0072375; P:medium-term memory; IMP:FlyBase.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IBA:GO_Central.
DR GO; GO:0050975; P:sensory perception of touch; IMP:FlyBase.
DR GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:GO_Central.
DR CDD; cd13718; PBP2_iGluR_NMDA_Nr2; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF391; NMDA RECEPTOR 2, ISOFORM C; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAL12478.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 484..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 366..723
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 370..428
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 902 AA; 102564 MW; AE84D3201F16202B CRC64;
MMNNEQFGHS TASAQYFLQL AGYLGIPVIS WNADNSGLER RASQSTLQLQ LAPSIEHQSA
AMLSILERYK WHQFSVVTSQ IAGHDDFVQA VRERVAEMQE HFKFTILNSI VVTRTSDLME
LVNSEARVML LYATQTEAIT ILRAAEEMKL TGENYVWVVS QSVIEKKDAH SQFPVGMLGV
HFDTSSAALM NEISNAIKIY SYGVEAYLTD PANRDRRLTT QSLSCEDEGR GRWDNGEIFF
KYLRNVSIEG DLNKPNIEFT ADGDLRSAEL KIMNLRPSAN NKNLVWEEIG VWKSWETQKL
DIRDIAWPGN SHAPPQGVPE KFHLKITFLE EAPYINLSPA DPVSGKCLMD RGVLCRVAAD
HEMAADIDVG QAHRNESFYQ CCSGFCIDLL EKFAEELGFT YELVRVEDGK WGTLENGKWN
GLIADLVNRK TDMVLTSLMI NTEREAVVDF SEPFMETGIA IVVAKRTGII SPTAFLEPFD
TASWMLVGIV AIQAATFMIF LFEWLSPSGY DMKLYLQNTN VTPYRFSLFR TYWLVWAVLF
QAAVHVDSPR GFTSRFMTNV WALFAVVFLA IYTANLAAFM ITREEFHEFS GLNDSRLVHP
FSHKPSFKFG TIPYSHTDST IHKYFNVMHN YMRQYNKTSV ADGVAAVLNG NLDSFIYDGT
VLDYLVAQDE DCRLMTVGSW YAMTGYGLAF SRNSKYVQMF NKRLLEFRAN GDLERLRRYW
MTGTCRPGKQ EHKSSDPLAL EQFLSAFLLL MAGILLAALL LLLEHVYFKY IRKRLAKKDG
GHCCALISLS MGKSLTFRGA VFEATEILKK HRCNDPICDT HLWKVKHELD MSRLRVRQLE
KVMDKHGIKA PQLRLASSSD LLNHHHLKER PPLLGNLSLA ASAQDLYRWS YKTEIAEMET
VL
//
