ID Q8NT40_CORGL Unreviewed; 453 AA.
AC Q8NT40; Q6M7Q3;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE SubName: Full=Gamma-aminobutyrate permease and related permeases {ECO:0000313|EMBL:BAB97863.1};
GN OrderedLocusNames=Cgl0470 {ECO:0000313|EMBL:BAB97863.1};
OS Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS JCM 1318 / LMG 3730 / NCIMB 10025).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=196627 {ECO:0000313|EMBL:BAB97863.1, ECO:0000313|Proteomes:UP000000582};
RN [1] {ECO:0000313|Proteomes:UP000000582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 /
RC NCIMB 10025 {ECO:0000313|Proteomes:UP000000582};
RX PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA Ikeda M., Nakagawa S.;
RT "The Corynebacterium glutamicum genome: features and impacts on
RT biotechnological processes.";
RL Appl. Microbiol. Biotechnol. 62:99-109(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000256|ARBA:ARBA00008583}.
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DR EMBL; BA000036; BAB97863.1; -; Genomic_DNA.
DR RefSeq; NP_599715.1; NC_003450.3.
DR AlphaFoldDB; Q8NT40; -.
DR STRING; 196627.cg0555; -.
DR KEGG; cgl:Cgl0470; -.
DR PATRIC; fig|196627.13.peg.468; -.
DR eggNOG; COG1113; Bacteria.
DR HOGENOM; CLU_007946_9_3_11; -.
DR OrthoDB; 5297508at2; -.
DR BioCyc; CORYNE:G18NG-10027-MONOMER; -.
DR Proteomes; UP000000582; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43495:SF2; D-SERINE_D-ALANINE_GLYCINE TRANSPORTER; 1.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000582};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 34..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..436
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 453 AA; 48691 MW; E8EEE4E962D9DC29 CRC64;
MSNRHLQLIA IGGAIGTGLF MGSGKTISVA GPSVILVYAI IGFMLFFVMR AMGELLLANL
NYKSLRDAVS DILGPGAGFV TGWTYWFCWI ATGMADIVAI TGYTQYWWPE IPLWLPGVLT
IALLFALNLA AVRLFGEMEF WFAIIKIVAI VSLIVVGLFM VVTAFESPNG TTAQFNNLIE
HGGFFPNGIT GFLAGFQIAI FAFVGIELAG TAAAETENPT KTLPRAINSI PIRIVVFYVL
ALAVIMMVTP WDQVRADNSP FVQMFALAGI PAAAGIINFV VITSAASSAN SGIFSTSRML
YGLSLEGAAP KRWSRLSKNL VPARGLTFSV ICLIPAVGLL YAGGTVIEAF TLITTVSSVL
FMVVWSYILV AYIVYRRNSP ELHKKSIFKM PGGVVMAVVV LVFFAAMLVV LSLEPDTRAA
LIATPVWFII LGIGWLSIGG AKGAKHRSQI TSH
//
