ID Q8PU38_METMA Unreviewed; 702 AA.
AC Q8PU38;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 146.
DE SubName: Full=Sensory transduction histidine kinases {ECO:0000313|EMBL:AAM32214.1};
GN OrderedLocusNames=MM_2518 {ECO:0000313|EMBL:AAM32214.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM32214.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM32214.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
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DR EMBL; AE008384; AAM32214.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8PU38; -.
DR KEGG; mma:MM_2518; -.
DR PATRIC; fig|192952.21.peg.2883; -.
DR eggNOG; arCOG02376; Archaea.
DR HOGENOM; CLU_000445_114_71_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AAM32214.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:AAM32214.1}.
FT DOMAIN 1..66
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 78..144
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 201..244
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 273..323
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 324..394
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 465..684
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 307..334
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 702 AA; 78462 MW; DA07E1E052081CF6 CRC64;
MLPECDGYEI CRILKNDPDY KFIPIIVISG FFEKPNKLKA TRCGADDFIQ KPIDRFELKT
RIKSLIRIKK NYEALQESES RYRQFFNNSP AVTLLVDPES YRIVDANDPA CAYYGYTYEE
MTAKKISDIN VFSEEKNKEI TRQVFLEKRG HFYSCHKLAS GEIRHVEVYI NTVNIRDKEL
FFINVYDITA SKKAERELIE SEEKFKQVVE LSVDGIIIGT DSGKIVDCNG AACRIFGYDK
EEILKLQVID LFPGDLNIIA HDITSCNKAA GEKTVERINQ KKDGTSFPAE VAARRVKLGN
EEGLIVYVRD ITERKKAEKA LKESEENFRT LVNNTLDGIL ILDFEGRVLA ANAAIGKMLG
MELEKVAGID IMKYLAPESV PVAVEDQINV LNGRGGYLSV YKSTSCNGEP LWIEGLGTKI
IYRGQPANIV VIRDITARKK AEEALINAKT AAEAANRTKS EFLTNMSHEL KTPLNSIIGF
SDLLIEGIAG PLNEKQSRYA GFISSNGKNL LNIINGILEL SKVESEGDEL TLQEFSVNES
INKSISTALP QILKKNIKLN YNSDSDPLCI FADENKFRQI MESLLNNAVK FTPEDGLIDI
SSKQEGGIVT IKVKDTGIGI PEDSLDKIFK PFIQLESSLS RTFEGTGLGL TLAKKYVEMH
GGNISVESKT GKGSSFKVEL PVNRQKTVRT TIQKLDQQIV ES
//
