ID Q8PWD2_METMA Unreviewed; 399 AA.
AC Q8PWD2;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Putative serine/threonine protein phosphatase {ECO:0000313|EMBL:AAM31353.1};
DE EC=3.1.3.16 {ECO:0000313|EMBL:AAM31353.1};
GN OrderedLocusNames=MM_1657 {ECO:0000313|EMBL:AAM31353.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM31353.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM31353.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
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DR EMBL; AE008384; AAM31353.1; -; Genomic_DNA.
DR RefSeq; WP_011033600.1; NC_003901.1.
DR AlphaFoldDB; Q8PWD2; -.
DR GeneID; 82160713; -.
DR KEGG; mma:MM_1657; -.
DR PATRIC; fig|192952.21.peg.1921; -.
DR eggNOG; arCOG01143; Archaea.
DR HOGENOM; CLU_052969_0_0_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11668; SERINE/THREONINE PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR11668:SF517; SERINE_THREONINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000313|EMBL:AAM31353.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT DOMAIN 174..353
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 399 AA; 45257 MW; CAB622AFF2B3389B CRC64;
MRYLVFLRGI PGSGKSTFVK EEGLEPYTIS SDTVRLLIKP PVLSVAGQPV TSQKINRRVW
GLIYSLIKCR MEEGEFTVLD ATNAGNADIA KYRSPVKAYR YEAFCVDFSD VSTELAKERN
MGRPAYEIVP ETVIEEMYAI IKRQSVPSFV TVIKPHEFRK RLQYNTPDFS NYKKIHHIGD
INGSYTALMK YLSCGLGDND LYIFLGDYAG RGNENSRVVK FLVSIMCRDN VVLLEGDNEK
RLCRPAAGEK QTRIEDFSDT TGILKELERE GALQDALKLC GKTVPCVYYK FHDKSVLVTH
GGLSSLPENL IFMGAEQMIN GVGEPEDVFL VAEHFNKNTN ENTYQVHGHR NPENLPVKNG
RTFNLSDESR KGSFLRTLTL DREGFDWQCI RKKNSFIQL
//
