ID Q8PYV1_METMA Unreviewed; 642 AA.
AC Q8PYV1;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=Dihydropyrimidinase {ECO:0000313|EMBL:AAM30446.1};
DE EC=3.5.2.2 {ECO:0000313|EMBL:AAM30446.1};
GN OrderedLocusNames=MM_0750 {ECO:0000313|EMBL:AAM30446.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM30446.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM30446.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
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DR EMBL; AE008384; AAM30446.1; -; Genomic_DNA.
DR RefSeq; WP_011032701.1; NC_003901.1.
DR AlphaFoldDB; Q8PYV1; -.
DR GeneID; 82159770; -.
DR KEGG; mma:MM_0750; -.
DR PATRIC; fig|192952.21.peg.892; -.
DR eggNOG; arCOG01513; Archaea.
DR HOGENOM; CLU_014140_1_0_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0004157; F:dihydropyrimidinase activity; IEA:UniProtKB-EC.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAM30446.1}.
FT DOMAIN 5..157
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 179..320
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
SQ SEQUENCE 642 AA; 69827 MW; 758FFE70478103A8 CRC64;
MHYSLGIDAG GTYTDAVLVR DSDGKIADSN KALTTYPDPL AGIKKVIDGL NPEYLKNIKL
VSVSTTLSTN TILEGNGFPV ALILIGDHPL EKEFPTGHVL FAGGGHNHNG EEISPLDLKA
IEKFALSVKD KVSAFAISSY FSTRNPEHEL KARDCIMKLT GLPAVCGHEL SQELGAYERS
VTAFLNAQLI PITRQFVKSI IADMTERGIN ARLLMLKCDG SVIGIKDALQ RPIETIFSGP
AASLVGASYL SGLQTCAVVD VGGTSTDISS IYMGVPDLSD DGAIVGGWKT RVRAIRMETT
ATGGDSHVWT VDRGLHLGPR RVMPLAVAAA QYQDFLNTLK RTPIPAREDL GENIQPTKFF
VRSGYTAGEI SKVESEVLGV IGDEPVSVND IKTLIRKDLH PQTLDSLIKK RLIQAIGFTP
TDALHVLGEY TAWNEEASRI GAERLARLMR MTPHEFCTSV KKKVARNMSL HLLSYILQGV
PHTAIEQILD GNYQAKFKLG VPVVLLGGPV RSHRKELEEF IDAEIIVPEH AEVGNAAGAL
AGKGIKRVEI LIRPASLMSP EKDFLVFAPG SRQRFDVYTE ALNVATELGK KLVEDYMKEC
GLSGDQVEIS IEKKTISPEG WNHPPMETNL LVMGIGMRRL HG
//
